| Title |
Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study
|
|---|---|
| Published in |
Rheumatology International, February 2007
|
| DOI | 10.1007/s00296-007-0304-y |
| Pubmed ID | |
| Authors |
Reto Widrig, Andy Suter, Reinhard Saller, Jörg Melzer |
| Abstract |
The use of topical preparations for symptom relief is common in osteoarthritis. The effects of ibuprofen (5%) and arnica (50 g tincture/100 g, DER 1:20), as gel preparations in patients with radiologically confirmed and symptomatically active osteoarthritis of interphalangeal joints of hands, were evaluated in a randomised, double-blind study in 204 patients, to ascertain differences in pain relief and hand function after 21 days' treatment. Diagnosis was according to established criteria; primary endpoints were pain intensity and hand function; statistical design was as per current regulatory guidelines for testing topical preparations. There were no differences between the two groups in pain and hand function improvements, or in any secondary end points evaluated. Adverse events were reported by six patients (6.1%) on ibuprofen and by five patients (4.8%) on arnica. Our results confirm that this preparation of arnica is not inferior to ibuprofen when treating osteoarthritis of hands. |
X Demographics
The data shown below were collected from the profiles of 35 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 26% |
| United Kingdom | 4 | 11% |
| New Zealand | 2 | 6% |
| Norway | 1 | 3% |
| Ireland | 1 | 3% |
| India | 1 | 3% |
| Comoros | 1 | 3% |
| Unknown | 16 | 46% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 30 | 86% |
| Scientists | 4 | 11% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | <1% |
| Unknown | 129 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 26 | 20% |
| Student > Master | 19 | 15% |
| Researcher | 15 | 12% |
| Other | 14 | 11% |
| Student > Doctoral Student | 8 | 6% |
| Other | 24 | 18% |
| Unknown | 24 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 42 | 32% |
| Pharmacology, Toxicology and Pharmaceutical Science | 14 | 11% |
| Agricultural and Biological Sciences | 11 | 8% |
| Nursing and Health Professions | 9 | 7% |
| Biochemistry, Genetics and Molecular Biology | 4 | 3% |
| Other | 20 | 15% |
| Unknown | 30 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 291. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 October 2023.
All research outputs
#119,169
of 25,243,120 outputs
Outputs from Rheumatology International
#2
of 2,437 outputs
Outputs of similar age
#153
of 88,244 outputs
Outputs of similar age from Rheumatology International
#1
of 7 outputs
Altmetric has tracked 25,243,120 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,437 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 88,244 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them