| Title |
Smoking and multiple sclerosis susceptibility
|
|---|---|
| Published in |
European Journal of Epidemiology, October 2013
|
| DOI | 10.1007/s10654-013-9853-4 |
| Pubmed ID | |
| Authors |
Anna Karin Hedström, Jan Hillert, Tomas Olsson, Lars Alfredsson |
| Abstract |
Smoking is one of the most established risk factors for multiple sclerosis (MS). The aim of this study was to investigate how age at smoking debut, duration, intensity and cumulative dose of smoking, and smoking cessation influence the association between smoking and MS risk. In two Swedish population-based case-control studies (7,883 cases, 9,264 controls), subjects with different smoking habits were compared regarding MS risk, by calculating odds ratios with 95% confidence intervals. We observed a clear dose response association between cumulative dose of smoking and MS risk (p value for trend <10(-35)). Both duration and intensity of smoking contributed independently to the increased risk of MS. However, the detrimental effect of smoking abates a decade after smoking cessation regardless of the cumulative dose of smoking. Age at smoking debut did not affect the association between smoking and MS. Smoking increases the risk of MS in a dose response manner. However, in contrary to several other risk factors for MS that seem to affect the risk only if the exposure takes place during a specific period in life, smoking affects MS risk regardless of age at exposure, and the detrimental effect slowly abates after smoking cessation. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 167 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Sweden | 1 | <1% |
| Unknown | 165 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 29 | 17% |
| Student > Bachelor | 26 | 16% |
| Student > Ph. D. Student | 25 | 15% |
| Researcher | 17 | 10% |
| Student > Doctoral Student | 15 | 9% |
| Other | 24 | 14% |
| Unknown | 31 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 49 | 29% |
| Neuroscience | 21 | 13% |
| Biochemistry, Genetics and Molecular Biology | 15 | 9% |
| Agricultural and Biological Sciences | 13 | 8% |
| Nursing and Health Professions | 8 | 5% |
| Other | 19 | 11% |
| Unknown | 42 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 March 2022.
All research outputs
#2,195,740
of 23,414,653 outputs
Outputs from European Journal of Epidemiology
#317
of 1,661 outputs
Outputs of similar age
#21,017
of 213,682 outputs
Outputs of similar age from European Journal of Epidemiology
#3
of 14 outputs
Altmetric has tracked 23,414,653 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,661 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 39.3. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 213,682 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.