Title |
Prevalence of cognitive impairment in older women with pelvic floor disorders
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Published in |
International Urogynecology Journal & Pelvic Floor Dysfunction, April 2017
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DOI | 10.1007/s00192-017-3322-7 |
Pubmed ID | |
Authors |
Cynelle Murray Kunkle, Melinda G. Abernethy, Lily R. Van Tongeren, Tola B. Fashokun, Edward J. Wright, Chi Chiung Grace Chen |
Abstract |
This study aimed to determine the prevalence of mild cognitive impairment (MCI) and early dementia among women >55 years seeking care for pelvic floor disorders (PFDs) and to describe the impact of cognitive impairment on condition-specific quality of life (QoL). We hypothesized that the prevalence of MCI would be at least 15% among this population. This was a cross-sectional study of English-speaking women >55 years presenting for evaluation of PFDs. We assessed baseline demographics and administered the Short Test of Mental Status (STMS) to screen for cognitive impairment. We predicted a sample of 196 would be needed for a precision of ±5% of the estimated sample prevalence in participants with PFDs. Chi-square tests were used to compare categorical variables and Student's t tests and analysis of variance (ANOVA) for continuous variables. Multivariate regression analysis was used to assess for any independent association with cognitive impairment and condition-specific QoL. Between July 2013 and July 2014, 211 participants were enrolled. The prevalence of MCI and early dementia were 15% [95% confidence interval (CI) 10.9-20.6; n = 32)] and 17% (95% CI 11.9-22.1; n = 36], respectively. Patients with MCI and early dementia had higher Patient Heath Questionnaire scores indicating greater depressive symptoms (p = 0.006) and higher overall Pelvic Floor Impact Questionnaire scores indicating worse condition-specific QoL (p = 0.008). MCI and early dementia were prevalent in our population seeking care for PFDs. Women with cognitive impairment experienced worse condition-specific QoL. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Scientists | 1 | 25% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 44 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 7 | 16% |
Student > Master | 5 | 11% |
Student > Ph. D. Student | 4 | 9% |
Other | 3 | 7% |
Librarian | 2 | 5% |
Other | 5 | 11% |
Unknown | 18 | 41% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 18% |
Psychology | 5 | 11% |
Nursing and Health Professions | 4 | 9% |
Sports and Recreations | 2 | 5% |
Environmental Science | 1 | 2% |
Other | 5 | 11% |
Unknown | 19 | 43% |