| Title |
Transcranial Direct Current Stimulation Enhances Recovery of Stereopsis in Adults With Amblyopia
|
|---|---|
| Published in |
Neurotherapeutics, October 2013
|
| DOI | 10.1007/s13311-013-0200-y |
| Pubmed ID | |
| Authors |
Daniel P. Spiegel, Jinrong Li, Robert F. Hess, Winston D. Byblow, Daming Deng, Minbin Yu, Benjamin Thompson |
| Abstract |
Amblyopia is a neurodevelopmental disorder of vision caused by abnormal visual experience during early childhood that is often considered to be untreatable in adulthood. Recently, it has been shown that a novel dichoptic videogame-based treatment for amblyopia can improve visual function in adult patients, at least in part, by reducing inhibition of inputs from the amblyopic eye to the visual cortex. Non-invasive anodal transcranial direct current stimulation has been shown to reduce the activity of inhibitory cortical interneurons when applied to the primary motor or visual cortex. In this double-blind, sham-controlled cross-over study we tested the hypothesis that anodal transcranial direct current stimulation of the visual cortex would enhance the therapeutic effects of dichoptic videogame-based treatment. A homogeneous group of 16 young adults (mean age 22.1 ± 1.1 years) with amblyopia were studied to compare the effect of dichoptic treatment alone and dichoptic treatment combined with visual cortex direct current stimulation on measures of binocular (stereopsis) and monocular (visual acuity) visual function. The combined treatment led to greater improvements in stereoacuity than dichoptic treatment alone, indicating that direct current stimulation of the visual cortex boosts the efficacy of dichoptic videogame-based treatment. This intervention warrants further evaluation as a novel therapeutic approach for adults with amblyopia. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 208 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | <1% |
| United Kingdom | 1 | <1% |
| New Zealand | 1 | <1% |
| Denmark | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 203 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 14% |
| Student > Master | 30 | 14% |
| Student > Bachelor | 26 | 13% |
| Researcher | 25 | 12% |
| Student > Postgraduate | 11 | 5% |
| Other | 39 | 19% |
| Unknown | 47 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 18% |
| Psychology | 30 | 14% |
| Neuroscience | 28 | 13% |
| Nursing and Health Professions | 17 | 8% |
| Agricultural and Biological Sciences | 11 | 5% |
| Other | 26 | 13% |
| Unknown | 59 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2016.
All research outputs
#7,355,930
of 25,373,627 outputs
Outputs from Neurotherapeutics
#698
of 1,308 outputs
Outputs of similar age
#62,517
of 219,852 outputs
Outputs of similar age from Neurotherapeutics
#7
of 13 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,308 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 219,852 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.