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Stakeholder Views on Pharmacogenomic Testing

Overview of attention for article published in Pharmacotherapy, October 2013
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Title
Stakeholder Views on Pharmacogenomic Testing
Published in
Pharmacotherapy, October 2013
DOI 10.1002/phar.1364
Pubmed ID
Authors

Haridarshan N. Patel, Iulia D. Ursan, Patrick M. Zueger, Larisa H. Cavallari, A. Simon Pickard

Abstract

Pharmacogenomics has an important role in the evolution of personalized medicine, and its widespread uptake may ultimately depend on the interests and perspectives of key players in health care. Our aim was to summarize studies on stakeholder perspectives and attitudes toward pharmacogenomic testing. Thus, we conducted a review of original research studies that reported stakeholder views on pharmacogenomic testing using a structured approach in PubMed, International Pharmaceutical Abstracts, Cumulative Index to Nursing and Allied Health Literature, and EMBASE. A standardized data abstraction form was developed that included stakeholder group of interest-patients, general public, providers, and payers. Stakeholder views regarding barriers to pharmacogenetic implementation were organized into the following themes: ancillary information-related, clinical, economic, educational, ethical or legal, medical mistrust, and practicality. Of 34 studies that met our inclusion criteria, 37 perspectives were reported (15 on providers, 9 on the general public, 9 on patients, and 4 on payers). The most common topics that arose in studies of providers related to clinical usefulness of genetic data (n=11) and educational needs (n=11). Among the general public, the most common concerns were medical mistrust (n=5), insufficient education (n=5), and practicality (n=5). The most prevalent issues from the patient perspective were ethical or legal (n=6) and economic (n=5) issues. Among payers, leading issues were practicality (n=4) and clinical usefulness (n=3). There was overlap in the topics and concerns across stakeholder perspectives, including lack of knowledge about pharmacogenomic testing. Views on issues related to privacy, cost, and test result dissemination varied by stakeholder perspective. Limited research had been conducted in underrepresented groups. Efforts to address the issues raised by stakeholders may facilitate the implementation of pharmacogenomic testing into clinical practice.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Unknown 83 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 19%
Researcher 14 16%
Student > Ph. D. Student 13 15%
Student > Bachelor 7 8%
Student > Doctoral Student 4 5%
Other 13 15%
Unknown 18 21%
Readers by discipline Count As %
Medicine and Dentistry 16 19%
Pharmacology, Toxicology and Pharmaceutical Science 10 12%
Biochemistry, Genetics and Molecular Biology 9 11%
Nursing and Health Professions 6 7%
Economics, Econometrics and Finance 6 7%
Other 14 16%
Unknown 24 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2013.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Pharmacotherapy
#2,250
of 2,502 outputs
Outputs of similar age
#169,430
of 224,530 outputs
Outputs of similar age from Pharmacotherapy
#22
of 23 outputs
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We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.