| Title |
Methodological quality of animal studies on neuroprotection in focal cerebral ischaemia
|
|---|---|
| Published in |
Journal of Neurology, September 2005
|
| DOI | 10.1007/s00415-005-0802-3 |
| Pubmed ID | |
| Authors |
H. Bart Worp, Peter Haan, Erik Morrema, Cor J. Kalkman |
| Abstract |
The recurrent failure of apparently promising neuroprotective drugs to improve outcome in trials of patients with acute ischaemic stroke may partially be explained by over-optimistic conclusions about efficacy as a result of methodological shortcomings in preclinical studies. We assessed the methodological quality of animal studies of five different neuroprotective agents that have been tested in 21 clinical trials including a total of more than 12,000 patients with acute ischaemic stroke. |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Netherlands | 1 | 2% |
| Unknown | 54 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 20% |
| Researcher | 7 | 13% |
| Student > Doctoral Student | 7 | 13% |
| Student > Bachelor | 6 | 11% |
| Professor | 4 | 7% |
| Other | 15 | 27% |
| Unknown | 6 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 34% |
| Agricultural and Biological Sciences | 12 | 21% |
| Neuroscience | 7 | 13% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Business, Management and Accounting | 1 | 2% |
| Other | 6 | 11% |
| Unknown | 7 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2013.
All research outputs
#5,482,860
of 22,729,647 outputs
Outputs from Journal of Neurology
#1,327
of 4,457 outputs
Outputs of similar age
#16,651
of 58,561 outputs
Outputs of similar age from Journal of Neurology
#3
of 17 outputs
Altmetric has tracked 22,729,647 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,457 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 58,561 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.