| Title |
Tardive dystonic syndrome induced by the calcium-channel blocker amlodipine
|
|---|---|
| Published in |
Journal of Neural Transmission, October 2013
|
| DOI | 10.1007/s00702-013-1108-8 |
| Pubmed ID | |
| Authors |
Dirk Dressler |
| Abstract |
Identification of drug exposure as a cause for dystonia is important since cessation of the causative agent offers a chance for remission. We describe two patients with a cranial, cervical, pharyngo-laryngeal and axial dystonia, akathisia, breathing dysrhythmias together with depression and anxiety. Both patients were started on the calcium channel blocker (CCB) amlodipine 1 month before symptom onset. They symptoms were non-acute and due to CCBs well-known D2 antagonism; hence they were classified as a tardive dystonic syndrome. Parkinsonism and depression have been described especially for the CCB flunarizine and cinnarizine. Tardive dystonia under CCB has rarely been reported. CCB exposure should be investigated in all dystonias with cranial, cervical, pharyngo-laryngeal and axial manifestations, especially when additional akathisia, Parkinsonism and depression are present. When CCB induction is suspected, CCB cessation may offer a chance for spontaneous remission. Whether CCB exposure can deteriorate, idiopathic dystonia is unclear. Therefore, CCB should best be avoided in patients with dystonia. |
Mendeley readers
The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 27 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 5 | 19% |
| Other | 4 | 15% |
| Student > Postgraduate | 4 | 15% |
| Student > Bachelor | 2 | 7% |
| Lecturer | 1 | 4% |
| Other | 4 | 15% |
| Unknown | 7 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 30% |
| Agricultural and Biological Sciences | 4 | 15% |
| Neuroscience | 3 | 11% |
| Nursing and Health Professions | 2 | 7% |
| Computer Science | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 8 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2013.
All research outputs
#15,766,926
of 23,418,312 outputs
Outputs from Journal of Neural Transmission
#1,287
of 1,803 outputs
Outputs of similar age
#132,529
of 214,236 outputs
Outputs of similar age from Journal of Neural Transmission
#11
of 21 outputs
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