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Mapping of Mitochondrial RNA-Protein Interactions by Digital RNase Footprinting

Overview of attention for article published in Cell Reports, October 2013
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Title
Mapping of Mitochondrial RNA-Protein Interactions by Digital RNase Footprinting
Published in
Cell Reports, October 2013
DOI 10.1016/j.celrep.2013.09.036
Pubmed ID
Authors

Ganqiang Liu, Timothy R. Mercer, Anne-Marie J. Shearwood, Stefan J. Siira, Moira E. Hibbs, John S. Mattick, Oliver Rackham, Aleksandra Filipovska

Abstract

Human mitochondrial DNA is transcribed as long polycistronic transcripts that encompass each strand of the genome and are processed subsequently into mature mRNAs, tRNAs, and rRNAs, necessitating widespread posttranscriptional regulation. Here, we establish methods for massively parallel sequencing and analyses of RNase-accessible regions of human mitochondrial RNA and thereby identify specific regions within mitochondrial transcripts that are bound by proteins. This approach provides a range of insights into the contribution of RNA-binding proteins to the regulation of mitochondrial gene expression.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
United Kingdom 1 1%
Unknown 86 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 29%
Researcher 16 18%
Professor > Associate Professor 9 10%
Professor 7 8%
Student > Master 7 8%
Other 13 14%
Unknown 12 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 38 42%
Agricultural and Biological Sciences 25 28%
Computer Science 5 6%
Medicine and Dentistry 4 4%
Engineering 3 3%
Other 5 6%
Unknown 10 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2013.
All research outputs
#22,778,604
of 25,394,764 outputs
Outputs from Cell Reports
#12,703
of 12,973 outputs
Outputs of similar age
#199,781
of 226,001 outputs
Outputs of similar age from Cell Reports
#144
of 157 outputs
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