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Analyzing gene expression data in mice with the Neuro Behavior Ontology

Overview of attention for article published in Mammalian Genome, November 2013
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Title
Analyzing gene expression data in mice with the Neuro Behavior Ontology
Published in
Mammalian Genome, November 2013
DOI 10.1007/s00335-013-9481-z
Pubmed ID
Authors

Robert Hoehndorf, John M. Hancock, Nigel W. Hardy, Ann-Marie Mallon, Paul N. Schofield, Georgios V. Gkoutos

Abstract

We have applied the Neuro Behavior Ontology (NBO), an ontology for the annotation of behavioral gene functions and behavioral phenotypes, to the annotation of more than 1,000 genes in the mouse that are known to play a role in behavior. These annotations can be explored by researchers interested in genes involved in particular behaviors and used computationally to provide insights into the behavioral phenotypes resulting from differences in gene expression. We developed the OntoFUNC tool and have applied it to enrichment analyses over the NBO to provide high-level behavioral interpretations of gene expression datasets. The resulting increase in the number of gene annotations facilitates the identification of behavioral or neurologic processes by assisting the formulation of hypotheses about the relationships between gene, processes, and phenotypic manifestations resulting from behavioral observations.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 7%
France 1 4%
Brazil 1 4%
Unknown 24 86%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 32%
Student > Master 6 21%
Student > Ph. D. Student 5 18%
Other 2 7%
Professor > Associate Professor 2 7%
Other 2 7%
Unknown 2 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 39%
Computer Science 5 18%
Biochemistry, Genetics and Molecular Biology 2 7%
Medicine and Dentistry 2 7%
Engineering 2 7%
Other 3 11%
Unknown 3 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 November 2013.
All research outputs
#18,353,475
of 22,729,647 outputs
Outputs from Mammalian Genome
#1,003
of 1,124 outputs
Outputs of similar age
#158,879
of 213,637 outputs
Outputs of similar age from Mammalian Genome
#6
of 6 outputs
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