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Current state and future of photodynamic therapy for the treatment of head and neck squamous cell carcinoma

Overview of attention for article published in World Journal of Otorhinolaryngology-Head and Neck Surgery, June 2016
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Title
Current state and future of photodynamic therapy for the treatment of head and neck squamous cell carcinoma
Published in
World Journal of Otorhinolaryngology-Head and Neck Surgery, June 2016
DOI 10.1016/j.wjorl.2016.05.011
Pubmed ID
Authors

Christina Mimikos, Gal Shafirstein, Hassan Arshad

Abstract

Photodynamic therapy has shown promise in the treatment of early head and neck squamous cell carcinoma (SCC). In photodynamic therapy (PDT), a light sensitive drug (photosensitizer) and visible light cause cancer cell death by the creation of singlet oxygen and free radicals, inciting an immune response, and vascular collapse. In this paper, we review several studies that demonstrate the effectiveness of PDT in the treatment of early stage SCC of the head and neck, with some showing a similar response rate to surgery. Two cases are presented to illustrate the effectiveness of PDT. Then, new advances are discussed including the discovery of STAT3 crosslinking as a potential biomarker for PDT response and interstitial PDT for locally advanced cancers.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 18%
Student > Ph. D. Student 6 14%
Researcher 5 11%
Student > Doctoral Student 3 7%
Student > Bachelor 3 7%
Other 10 23%
Unknown 9 20%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 8 18%
Medicine and Dentistry 7 16%
Biochemistry, Genetics and Molecular Biology 4 9%
Chemistry 4 9%
Physics and Astronomy 4 9%
Other 6 14%
Unknown 11 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2017.
All research outputs
#20,674,485
of 25,394,764 outputs
Outputs from World Journal of Otorhinolaryngology-Head and Neck Surgery
#115
of 157 outputs
Outputs of similar age
#270,021
of 353,760 outputs
Outputs of similar age from World Journal of Otorhinolaryngology-Head and Neck Surgery
#5
of 6 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 157 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,760 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.