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Acetylcholinesterase inhibition activity of acetylated depsidones from Lobaria pulmonaria

Overview of attention for article published in Natural Product Research, October 2011
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1 X user

Citations

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Title
Acetylcholinesterase inhibition activity of acetylated depsidones from Lobaria pulmonaria
Published in
Natural Product Research, October 2011
DOI 10.1080/14786419.2011.585989
Pubmed ID
Authors

Boris Pejin, Giuseppina Tommonaro, Carmine Iodice, Vele Tesevic, Vlatka Vajs

Abstract

As part of our ongoing project of new acetylcholinesterase inhibitors from lower marine and terrestrial species, a phytochemical investigation was conducted on a foliose lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), from Bosnia and Herzegovina. The study led to the isolation of a mixture of acetylated depsidones which showed a moderate activity (0.5 µg) in the acetylcholinesterase inhibition test on Thin-layer chromatography plate. Our results indicate for the first time the significance of depsidones, highly specific metabolites from lichen species, in searching for these inhibitors which still represent the best drugs currently available for the management of Alzheimer's disease.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 25%
Other 3 19%
Student > Ph. D. Student 2 13%
Student > Doctoral Student 1 6%
Lecturer 1 6%
Other 2 13%
Unknown 3 19%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 5 31%
Agricultural and Biological Sciences 4 25%
Environmental Science 1 6%
Chemistry 1 6%
Medicine and Dentistry 1 6%
Other 0 0%
Unknown 4 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2013.
All research outputs
#17,283,763
of 25,371,288 outputs
Outputs from Natural Product Research
#907
of 2,395 outputs
Outputs of similar age
#104,433
of 148,548 outputs
Outputs of similar age from Natural Product Research
#19
of 31 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,395 research outputs from this source. They receive a mean Attention Score of 2.2. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 148,548 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.