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Mendeley readers
Attention Score in Context
| Title |
MRI‐Visual Order–Disorder Micellar Nanostructures for Smart Cancer Theranostics
|
|---|---|
| Published in |
Advanced Healthcare Materials, August 2013
|
| DOI | 10.1002/adhm.201300225 |
| Pubmed ID | |
| Authors |
Hirak K. Patra, Nisar Ul Khaliq, Thobias Romu, Emilia Wiechec, Magnus Borga, Anthony P. F. Turner, Ashutosh Tiwari |
| Abstract |
The development of MRI-visual order-disorder structures for cancer nanomedicine explores a pH-triggered mechanism for theragnosis of tumor hallmark functions. Superparamagnetic iron oxide nanoparticles (SPIONs) stabilized with amphiphilic poly(styrene)-b-poly(acrylic acid)-doxorubicin with folic acid (FA) surfacing are employed as a multi-functional approach to specifically target, diagnose, and deliver drugs via a single nanoscopic platform for cancer therapy. The functional aspects of the micellar nanocomposite is investigated in vitro using human breast SkBr3 and colon cancer HCT116 cell lines for the delivery, release, localization, and anticancer activity of the drug. For the first time, concentration-dependent T2 -weighted MRI contrast for a monolayer of clustered cancer cells is shown. The pH tunable order-disorder transition of the core-shell structure induces the relative changes in MRI contrast. The outcomes elucidate the potential of this material for smart cancer theranostics by delivering non-invasive real-time diagnosis, targeted therapy, and monitoring the course and response of the action before, during, and after the treatment regimen. |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 52 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 19% |
| Student > Ph. D. Student | 10 | 19% |
| Student > Master | 7 | 13% |
| Unspecified | 5 | 10% |
| Professor | 4 | 8% |
| Other | 7 | 13% |
| Unknown | 9 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 11 | 21% |
| Medicine and Dentistry | 5 | 10% |
| Unspecified | 5 | 10% |
| Biochemistry, Genetics and Molecular Biology | 4 | 8% |
| Physics and Astronomy | 3 | 6% |
| Other | 13 | 25% |
| Unknown | 11 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2013.
All research outputs
#4,584,331
of 24,602,766 outputs
Outputs from Advanced Healthcare Materials
#695
of 2,726 outputs
Outputs of similar age
#37,675
of 205,065 outputs
Outputs of similar age from Advanced Healthcare Materials
#11
of 31 outputs
Altmetric has tracked 24,602,766 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,726 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 205,065 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.