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Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging

Overview of attention for article published in Neurobiology of Aging, May 2010
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
policy
1 policy source
patent
1 patent
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
869 Dimensions

Readers on

mendeley
514 Mendeley
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Title
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
Published in
Neurobiology of Aging, May 2010
DOI 10.1016/j.neurobiolaging.2010.04.007
Pubmed ID
Authors

Christopher C. Rowe, Kathryn A. Ellis, Miroslava Rimajova, Pierrick Bourgeat, Kerryn E. Pike, Gareth Jones, Jurgen Fripp, Henri Tochon-Danguy, Laurence Morandeau, Graeme O'Keefe, Roger Price, Parnesh Raniga, Peter Robins, Oscar Acosta, Nat Lenzo, Cassandra Szoeke, Olivier Salvado, Richard Head, Ralph Martins, Colin L. Masters, David Ames, Victor L. Villemagne

Abstract

The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging, a participant of the worldwide Alzheimer's Disease Neuroimaging Initiative (ADNI), performed (11)C-Pittsburgh Compound B (PiB) scans in 177 healthy controls (HC), 57 mild cognitive impairment (MCI) subjects, and 53 mild Alzheimer's disease (AD) patients. High PiB binding was present in 33% of HC (49% in ApoE-epsilon4 carriers vs 21% in noncarriers) and increased with age, most strongly in epsilon4 carriers. 18% of HC aged 60-69 had high PiB binding rising to 65% in those over 80 years. Subjective memory complaint was only associated with elevated PiB binding in epsilon4 carriers. There was no correlation with cognition in HC or MCI. PiB binding in AD was unrelated to age, hippocampal volume or memory. Beta-amyloid (Abeta) deposition seems almost inevitable with advanced age, amyloid burden is similar at all ages in AD, and secondary factors or downstream events appear to play a more direct role than total beta amyloid burden in hippocampal atrophy and cognitive decline.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 514 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 9 2%
United Kingdom 2 <1%
Germany 1 <1%
Czechia 1 <1%
Netherlands 1 <1%
Denmark 1 <1%
Italy 1 <1%
Unknown 498 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 93 18%
Researcher 87 17%
Student > Master 61 12%
Student > Bachelor 38 7%
Student > Doctoral Student 37 7%
Other 96 19%
Unknown 102 20%
Readers by discipline Count As %
Medicine and Dentistry 101 20%
Neuroscience 83 16%
Psychology 62 12%
Agricultural and Biological Sciences 44 9%
Biochemistry, Genetics and Molecular Biology 23 4%
Other 77 15%
Unknown 124 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2020.
All research outputs
#1,055,932
of 25,374,917 outputs
Outputs from Neurobiology of Aging
#132
of 4,418 outputs
Outputs of similar age
#3,095
of 103,376 outputs
Outputs of similar age from Neurobiology of Aging
#1
of 35 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,418 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,376 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.