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Deciphering Hematopoietic Stem Cells in Their Niches: A Critical Appraisal of Genetic Models, Lineage Tracing, and Imaging Strategies

Overview of attention for article published in Cell Stem Cell, November 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

news
2 news outlets
twitter
3 X users
patent
1 patent

Citations

dimensions_citation
149 Dimensions

Readers on

mendeley
371 Mendeley
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Title
Deciphering Hematopoietic Stem Cells in Their Niches: A Critical Appraisal of Genetic Models, Lineage Tracing, and Imaging Strategies
Published in
Cell Stem Cell, November 2013
DOI 10.1016/j.stem.2013.10.010
Pubmed ID
Authors

Chacko Joseph, Julie M. Quach, Carl R. Walkley, Steven W. Lane, Cristina Lo Celso, Louise E. Purton

Abstract

In recent years, technical developments in mouse genetics and imaging equipment have substantially advanced our understanding of hematopoietic stem cells (HSCs) and their niche. The availability of numerous Cre strains for targeting HSCs and microenvironmental cells provides extensive flexibility in experimental design, but it can also pose significant challenges due to strain-specific differences in cell specificity. Here we outline various genetic approaches for isolating, detecting, and ablating HSCs and niche components and provide a guide for advantages and caveats to consider. We also discuss opportunities and limitations presented by imaging technologies that allow investigation of HSC behavior in situ.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 371 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 1%
Germany 2 <1%
United Kingdom 2 <1%
Sweden 1 <1%
Netherlands 1 <1%
Spain 1 <1%
Australia 1 <1%
Unknown 359 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 98 26%
Researcher 85 23%
Student > Master 33 9%
Student > Bachelor 26 7%
Student > Doctoral Student 19 5%
Other 55 15%
Unknown 55 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 117 32%
Biochemistry, Genetics and Molecular Biology 82 22%
Medicine and Dentistry 50 13%
Immunology and Microbiology 33 9%
Engineering 6 2%
Other 17 5%
Unknown 66 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 July 2023.
All research outputs
#1,735,037
of 25,371,288 outputs
Outputs from Cell Stem Cell
#1,094
of 2,823 outputs
Outputs of similar age
#15,923
of 226,635 outputs
Outputs of similar age from Cell Stem Cell
#23
of 42 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,823 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 48.5. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,635 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.