| Title |
The SLC38 family of sodium–amino acid co-transporters
|
|---|---|
| Published in |
Pflügers Archiv - European Journal of Physiology, November 2013
|
| DOI | 10.1007/s00424-013-1393-y |
| Pubmed ID | |
| Authors |
Stefan Bröer |
| Abstract |
Transporters of the SLC38 family are found in all cell types of the body. They mediate Na(+)-dependent net uptake and efflux of small neutral amino acids. As a result they are particularly expressed in cells that grow actively, or in cells that carry out significant amino acid metabolism, such as liver, kidney and brain. SLC38 transporters occur in membranes that face intercellular space or blood vessels, but do not occur in the apical membrane of absorptive epithelia. In the placenta, they play a significant role in the transfer of amino acids to the foetus. Members of the SLC38 family are highly regulated in response to amino acid depletion, hypertonicity and hormonal stimuli. SLC38 transporters play an important role in amino acid signalling and have been proposed to act as transceptors independent of their transport function. The structure of SLC38 transporters is characterised by the 5 + 5 inverted repeat fold, which is observed in a wide variety of transport proteins. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Portugal | 1 | <1% |
| Switzerland | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 147 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 32 | 21% |
| Researcher | 25 | 17% |
| Student > Master | 19 | 13% |
| Student > Bachelor | 17 | 11% |
| Professor | 9 | 6% |
| Other | 20 | 13% |
| Unknown | 29 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 47 | 31% |
| Agricultural and Biological Sciences | 39 | 26% |
| Immunology and Microbiology | 10 | 7% |
| Medicine and Dentistry | 8 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
| Other | 12 | 8% |
| Unknown | 30 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 January 2018.
All research outputs
#7,601,772
of 23,815,455 outputs
Outputs from Pflügers Archiv - European Journal of Physiology
#452
of 1,973 outputs
Outputs of similar age
#70,103
of 217,592 outputs
Outputs of similar age from Pflügers Archiv - European Journal of Physiology
#10
of 23 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,973 research outputs from this source. They receive a mean Attention Score of 5.0. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 217,592 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.