Title |
Significant role of ADRB3 rs4994 towards the development of coronary artery disease
|
---|---|
Published in |
Coronary artery disease, January 2014
|
DOI | 10.1097/mca.0000000000000056 |
Pubmed ID | |
Authors |
Surendra Kumar, Avshesh Mishra, Anshika Srivastava, Tulika Mittal, Naveen Garg, Balraj Mittal |
Abstract |
Coronary artery disease (CAD) is the most common type of heart disease and cause of heart attacks. It has been proposed that both the susceptibility to disease and the interindividual variability in response to treatment relates in part to genetic polymorphisms, particularly those polymorphisms for neurotransmitter and drug receptors. Common functional polymorphisms in β-adrenergic receptor genes (ADRB) have been associated with heart failure phenotypes. Therefore, the purpose of the present study was to explore the association of genetic variants in ADRB3 (C190T or Trp64Arg) ADRB1 (C1165G or Arg389Gly), and ADRA2A (C-1291G) with CAD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Nigeria | 1 | 33% |
India | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 19% |
Student > Bachelor | 3 | 11% |
Student > Ph. D. Student | 3 | 11% |
Student > Master | 3 | 11% |
Professor | 2 | 7% |
Other | 4 | 15% |
Unknown | 7 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 37% |
Biochemistry, Genetics and Molecular Biology | 3 | 11% |
Agricultural and Biological Sciences | 3 | 11% |
Business, Management and Accounting | 1 | 4% |
Arts and Humanities | 1 | 4% |
Other | 2 | 7% |
Unknown | 7 | 26% |