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A Randomized Trial of Dietary Sodium Restriction in CKD

Overview of attention for article published in Journal of the American Society of Nephrology, November 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Citations

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234 Mendeley
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1 CiteULike
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Title
A Randomized Trial of Dietary Sodium Restriction in CKD
Published in
Journal of the American Society of Nephrology, November 2013
DOI 10.1681/asn.2013030285
Pubmed ID
Authors

Emma J. McMahon, Judith D. Bauer, Carmel M. Hawley, Nicole M. Isbel, Michael Stowasser, David W. Johnson, Katrina L. Campbell

Abstract

There is a paucity of quality evidence regarding the effects of sodium restriction in patients with CKD, particularly in patients with pre-end stage CKD, where controlling modifiable risk factors may be especially important for delaying CKD progression and cardiovascular events. We conducted a double-blind placebo-controlled randomized crossover trial assessing the effects of high versus low sodium intake on ambulatory BP, 24-hour protein and albumin excretion, fluid status (body composition monitor), renin and aldosterone levels, and arterial stiffness (pulse wave velocity and augmentation index) in 20 adult patients with hypertensive stage 3-4 CKD as phase 1 of the LowSALT CKD study. Overall, salt restriction resulted in statistically significant and clinically important reductions in BP (mean reduction of systolic/diastolic BP, 10/4 mm Hg; 95% confidence interval, 5 to 15 /1 to 6 mm Hg), extracellular fluid volume, albuminuria, and proteinuria in patients with moderate-to-severe CKD. The magnitude of change was more pronounced than the magnitude reported in patients without CKD, suggesting that patients with CKD are particularly salt sensitive. Although studies with longer intervention times and larger sample sizes are needed to confirm these benefits, this study indicates that sodium restriction should be emphasized in the management of patients with CKD as a means to reduce cardiovascular risk and risk for CKD progression.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 234 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
Malaysia 1 <1%
France 1 <1%
Korea, Republic of 1 <1%
United States 1 <1%
Unknown 229 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 39 17%
Student > Bachelor 30 13%
Researcher 22 9%
Other 15 6%
Professor 15 6%
Other 58 25%
Unknown 55 24%
Readers by discipline Count As %
Medicine and Dentistry 88 38%
Nursing and Health Professions 28 12%
Agricultural and Biological Sciences 13 6%
Biochemistry, Genetics and Molecular Biology 10 4%
Pharmacology, Toxicology and Pharmaceutical Science 7 3%
Other 26 11%
Unknown 62 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 134. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2018.
All research outputs
#310,049
of 25,373,627 outputs
Outputs from Journal of the American Society of Nephrology
#118
of 5,680 outputs
Outputs of similar age
#2,408
of 228,787 outputs
Outputs of similar age from Journal of the American Society of Nephrology
#3
of 57 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,680 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,787 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.