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Enhanced Gametocyte Formation in Erythrocyte Progenitor Cells: A Site-Specific Adaptation by Plasmodium falciparum

Overview of attention for article published in Journal of Infectious Diseases, July 2013
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Title
Enhanced Gametocyte Formation in Erythrocyte Progenitor Cells: A Site-Specific Adaptation by Plasmodium falciparum
Published in
Journal of Infectious Diseases, July 2013
DOI 10.1093/infdis/jit309
Pubmed ID
Authors

Christopher L. Peatey, Jolanta A. Watson, Katharine R. Trenholme, Christopher L. Brown, Lars Nielson, Marko Guenther, Nicholas Timmins, Gregory S. Watson, Donald L. Gardiner

Abstract

Gametocytogenesis by Plasmodium falciparum is essential for transmission of the parasite from human to mosquito, yet developing gametocytes lack expression of surface proteins required for cytoadherence. Therefore, elimination from the circulation should occur unless they are sequestered in regions of low blood flow such as the extracellular spaces of the bone marrow. Our data indicate that gametocytogenesis is enhanced in the presence of erythroid progenitors found within the bone marrow. Furthermore, atomic force microscopy indicates that developing gametocytes undergo remarkable shifts in their erythrocyte membrane elasticity, which may allow them to be retained within the bone marrow until maturation.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Unknown 52 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 31%
Student > Ph. D. Student 16 30%
Student > Master 4 7%
Student > Bachelor 2 4%
Student > Doctoral Student 2 4%
Other 4 7%
Unknown 9 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 31%
Biochemistry, Genetics and Molecular Biology 13 24%
Immunology and Microbiology 4 7%
Medicine and Dentistry 3 6%
Computer Science 2 4%
Other 4 7%
Unknown 11 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2013.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Journal of Infectious Diseases
#13,624
of 14,794 outputs
Outputs of similar age
#157,132
of 206,558 outputs
Outputs of similar age from Journal of Infectious Diseases
#117
of 140 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,794 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.4. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,558 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.