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Deep conservation of cis-regulatory elements in metazoans

Overview of attention for article published in Philosophical Transactions of the Royal Society B: Biological Sciences, December 2013
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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3 X users
wikipedia
1 Wikipedia page

Citations

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27 Dimensions

Readers on

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102 Mendeley
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Title
Deep conservation of cis-regulatory elements in metazoans
Published in
Philosophical Transactions of the Royal Society B: Biological Sciences, December 2013
DOI 10.1098/rstb.2013.0020
Pubmed ID
Authors

Ignacio Maeso, Manuel Irimia, Juan J. Tena, Fernando Casares, José Luis Gómez-Skarmeta

Abstract

Despite the vast morphological variation observed across phyla, animals share multiple basic developmental processes orchestrated by a common ancestral gene toolkit. These genes interact with each other building complex gene regulatory networks (GRNs), which are encoded in the genome by cis-regulatory elements (CREs) that serve as computational units of the network. Although GRN subcircuits involved in ancient developmental processes are expected to be at least partially conserved, identification of CREs that are conserved across phyla has remained elusive. Here, we review recent studies that revealed such deeply conserved CREs do exist, discuss the difficulties associated with their identification and describe new approaches that will facilitate this search.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Germany 2 2%
Spain 1 <1%
Thailand 1 <1%
Unknown 96 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 25%
Researcher 22 22%
Student > Master 10 10%
Student > Bachelor 7 7%
Professor > Associate Professor 5 5%
Other 16 16%
Unknown 16 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 45 44%
Biochemistry, Genetics and Molecular Biology 30 29%
Computer Science 2 2%
Environmental Science 1 <1%
Earth and Planetary Sciences 1 <1%
Other 3 3%
Unknown 20 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2018.
All research outputs
#7,355,005
of 25,371,288 outputs
Outputs from Philosophical Transactions of the Royal Society B: Biological Sciences
#4,105
of 7,095 outputs
Outputs of similar age
#80,657
of 320,491 outputs
Outputs of similar age from Philosophical Transactions of the Royal Society B: Biological Sciences
#52
of 80 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 7,095 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.7. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,491 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.