↓ Skip to main content

Reconstructing the Population Genetic History of the Caribbean

Overview of attention for article published in PLoS Genetics, November 2013
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
1 news outlet
blogs
9 blogs
twitter
64 X users
facebook
4 Facebook pages
wikipedia
1 Wikipedia page
googleplus
3 Google+ users
reddit
1 Redditor

Citations

dimensions_citation
305 Dimensions

Readers on

mendeley
399 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Reconstructing the Population Genetic History of the Caribbean
Published in
PLoS Genetics, November 2013
DOI 10.1371/journal.pgen.1003925
Pubmed ID
Authors

Andrés Moreno-Estrada, Simon Gravel, Fouad Zakharia, Jacob L. McCauley, Jake K. Byrnes, Christopher R. Gignoux, Patricia A. Ortiz-Tello, Ricardo J. Martínez, Dale J. Hedges, Richard W. Morris, Celeste Eng, Karla Sandoval, Suehelay Acevedo-Acevedo, Paul J. Norman, Zulay Layrisse, Peter Parham, Juan Carlos Martínez-Cruzado, Esteban González Burchard, Michael L. Cuccaro, Eden R. Martin, Carlos D. Bustamante

Abstract

The Caribbean basin is home to some of the most complex interactions in recent history among previously diverged human populations. Here, we investigate the population genetic history of this region by characterizing patterns of genome-wide variation among 330 individuals from three of the Greater Antilles (Cuba, Puerto Rico, Hispaniola), two mainland (Honduras, Colombia), and three Native South American (Yukpa, Bari, and Warao) populations. We combine these data with a unique database of genomic variation in over 3,000 individuals from diverse European, African, and Native American populations. We use local ancestry inference and tract length distributions to test different demographic scenarios for the pre- and post-colonial history of the region. We develop a novel ancestry-specific PCA (ASPCA) method to reconstruct the sub-continental origin of Native American, European, and African haplotypes from admixed genomes. We find that the most likely source of the indigenous ancestry in Caribbean islanders is a Native South American component shared among inland Amazonian tribes, Central America, and the Yucatan peninsula, suggesting extensive gene flow across the Caribbean in pre-Columbian times. We find evidence of two pulses of African migration. The first pulse--which today is reflected by shorter, older ancestry tracts--consists of a genetic component more similar to coastal West African regions involved in early stages of the trans-Atlantic slave trade. The second pulse--reflected by longer, younger tracts--is more similar to present-day West-Central African populations, supporting historical records of later transatlantic deportation. Surprisingly, we also identify a Latino-specific European component that has significantly diverged from its parental Iberian source populations, presumably as a result of small European founder population size. We demonstrate that the ancestral components in admixed genomes can be traced back to distinct sub-continental source populations with far greater resolution than previously thought, even when limited pre-Columbian Caribbean haplotypes have survived.

X Demographics

X Demographics

The data shown below were collected from the profiles of 64 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 399 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 8 2%
Germany 3 <1%
Spain 2 <1%
Brazil 1 <1%
Finland 1 <1%
Denmark 1 <1%
Austria 1 <1%
Canada 1 <1%
Philippines 1 <1%
Other 0 0%
Unknown 380 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 99 25%
Researcher 88 22%
Student > Master 44 11%
Student > Bachelor 40 10%
Other 18 5%
Other 61 15%
Unknown 49 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 154 39%
Biochemistry, Genetics and Molecular Biology 89 22%
Medicine and Dentistry 24 6%
Social Sciences 23 6%
Computer Science 14 4%
Other 39 10%
Unknown 56 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 114. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2023.
All research outputs
#370,361
of 25,589,756 outputs
Outputs from PLoS Genetics
#209
of 8,986 outputs
Outputs of similar age
#2,833
of 224,974 outputs
Outputs of similar age from PLoS Genetics
#3
of 182 outputs
Altmetric has tracked 25,589,756 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,986 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.8. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,974 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 182 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.