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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Biodegradable Oxamide‐Phenylene‐Based Mesoporous Organosilica Nanoparticles with Unprecedented Drug Payloads for Delivery in Cells
|
|---|---|
| Published in |
Chemistry - A European Journal, June 2016
|
| DOI | 10.1002/chem.201601714 |
| Pubmed ID | |
| Authors |
Jonas G. Croissant, Yevhen Fatieiev, Khachatur Julfakyan, Jie Lu, Abdul‐Hamid Emwas, Dalaver H. Anjum, Haneen Omar, Fuyuhiko Tamanoi, Jeffrey I. Zink, Niveen M. Khashab |
| Abstract |
We describe biodegradable mesoporous hybrid NPs in the presence of proteins, and its application for drug delivery. We synthesized oxamide-phenylene-based mesoporous organosilica nanoparticles (MON) in the absence of silica source which had a remarkably high organic content with a high surface area. Oxamide functions provided biodegradability in the presence of trypsin model proteins. MON displayed exceptionally high payloads of hydrophilic and hydrophobic drugs (up to 84 wt%), and a unique zero premature leakage without the pore capping, unlike mesoporous silica. MON were biocompatible and internalized into cancer cells for drug delivery. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Saudi Arabia | 1 | 2% |
| Unknown | 57 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 17% |
| Researcher | 8 | 14% |
| Student > Bachelor | 8 | 14% |
| Student > Doctoral Student | 6 | 10% |
| Student > Master | 5 | 8% |
| Other | 7 | 12% |
| Unknown | 15 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 24 | 41% |
| Materials Science | 3 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Agricultural and Biological Sciences | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 18 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2022.
All research outputs
#5,015,432
of 24,577,646 outputs
Outputs from Chemistry - A European Journal
#3,754
of 22,911 outputs
Outputs of similar age
#83,994
of 358,543 outputs
Outputs of similar age from Chemistry - A European Journal
#70
of 370 outputs
Altmetric has tracked 24,577,646 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,911 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 358,543 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 370 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.