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ApoA‐I mutations, L202P and K131del, in HDL from heterozygotes with low HDL‐C

Overview of attention for article published in PROTEOMICS - Clinical Applications, February 2014
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Title
ApoA‐I mutations, L202P and K131del, in HDL from heterozygotes with low HDL‐C
Published in
PROTEOMICS - Clinical Applications, February 2014
DOI 10.1002/prca.201300014
Pubmed ID
Authors

Stefan Ljunggren, Johannes H. M. Levels, Maria V. Turkina, Sofie Sundberg, Andrea E. Bochem, Kees Hovingh, Adriaan G. Holleboom, Mats Lindahl, Jan Albert Kuivenhoven, Helen Karlsson

Abstract

Mutations in apolipoprotein A-I (apoA-I) may affect plasma high-density lipoprotein (HDL) cholesterol levels and the risk for cardiovascular disease but little is known about the presence and effects of circulating apoA-I variants. This study investigates whether the apoA-I mutations, apoA-I(L202P) and apoA-I(K131del) , are present on plasma HDL particles derived from heterozygote carriers and whether this is associated to changes in HDL protein composition.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 7%
Unknown 13 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 29%
Researcher 3 21%
Student > Doctoral Student 2 14%
Professor 1 7%
Other 1 7%
Other 0 0%
Unknown 3 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 29%
Medicine and Dentistry 3 21%
Biochemistry, Genetics and Molecular Biology 1 7%
Philosophy 1 7%
Unknown 5 36%