↓ Skip to main content

Grape seed extract suppresses MDA-MB231 breast cancer cell migration and invasion

Overview of attention for article published in European Journal of Nutrition, June 2013
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

news
1 news outlet
twitter
3 X users
video
1 YouTube creator

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
49 Mendeley
Title
Grape seed extract suppresses MDA-MB231 breast cancer cell migration and invasion
Published in
European Journal of Nutrition, June 2013
DOI 10.1007/s00394-013-0542-6
Pubmed ID
Authors

Simona Dinicola, Alessia Pasqualato, Alessandra Cucina, Pierpaolo Coluccia, Francesca Ferranti, Rita Canipari, Angela Catizone, Sara Proietti, Fabrizio D’Anselmi, Giulia Ricci, Alessandro Palombo, Mariano Bizzarri

Abstract

Breast cancer remains a leading cause of mortality among women. In metastasis, cascade migration of cancer cells and invasion of extracellular matrix (ECM) represent critical steps. Urokinase-type plasminogen activator (uPA), as well as metalloproteinases MMP-2 and MMP-9, strongly contribute to ECM remodelling, thus becoming associated with tumour migration and invasion. In addition, the high expression of cytoskeletal (CSK) proteins, as fascin, has been correlated with clinically aggressive metastatic tumours, and CSK proteins are thought to affect the migration of cancer cells. Consumption of fruits and vegetables, characterized by high procyanidin content, has been associated to a reduced mortality for breast cancer. Therefore, we investigated the biological effect of grape seed extract (GSE) on the highly metastatic MDA-MB231 breast cancer cell line, focusing on studying GSE ability in inhibiting two main metastatic processes, i.e., cell migration and invasion.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 12%
Other 5 10%
Researcher 5 10%
Student > Ph. D. Student 5 10%
Student > Bachelor 4 8%
Other 8 16%
Unknown 16 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 16%
Medicine and Dentistry 7 14%
Agricultural and Biological Sciences 3 6%
Nursing and Health Professions 3 6%
Arts and Humanities 2 4%
Other 6 12%
Unknown 20 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2020.
All research outputs
#2,223,000
of 24,133,587 outputs
Outputs from European Journal of Nutrition
#556
of 2,502 outputs
Outputs of similar age
#19,030
of 200,927 outputs
Outputs of similar age from European Journal of Nutrition
#5
of 21 outputs
Altmetric has tracked 24,133,587 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,502 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.1. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 200,927 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.