Title |
Vitamin E and selenium supplementation in geriatric patients
|
---|---|
Published in |
Biological Trace Element Research, April 1985
|
DOI | 10.1007/bf02916538 |
Pubmed ID | |
Authors |
Matti Tolonen, Markku Halme, Seppo Sarna |
Abstract |
Sodium selenate (8 mg/d), organic selenium (50 μg/d) andd-alpha-tocopherol acetate (400 mg/d) were administered for 1 yr to 15 geriatric patients. Fifteen comparable controls received placebo. The mean age of both groups was 76 yr. The patients were assessed every 2 mo independently by two nurses using the Sandoz Clinical Assessment Geriatric-scale (SCAG). The propositae, showed significant improvement in the following SCAG parameters: depression, anxiety, self-care, mental alertness, emotional lability, motivation and initiative, hostility, interest in the environment, fatigue, anorexia, and general impression. A distinct improvement of the general condition was noticed after only 2 mo and the improvement continued up to the end of the 1-yr study period. The high selenium and vitamin E doses were well tolerated; there were no side effects whatsoever. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 3 | 30% |
Lecturer | 2 | 20% |
Student > Master | 2 | 20% |
Student > Doctoral Student | 1 | 10% |
Lecturer > Senior Lecturer | 1 | 10% |
Other | 0 | 0% |
Unknown | 1 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 4 | 40% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 20% |
Environmental Science | 1 | 10% |
Sports and Recreations | 1 | 10% |
Engineering | 1 | 10% |
Other | 0 | 0% |
Unknown | 1 | 10% |