| Title |
Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis
|
|---|---|
| Published in |
Journal of Microbiology, April 2017
|
| DOI | 10.1007/s12275-017-6630-1 |
| Pubmed ID | |
| Authors |
Ji-Chan Jang, Yong-Gyun Jung, Jungil Choi, Hyunju Jung, Sungweon Ryoo |
| Abstract |
This study aimed to provide information that bedaquilline is significantly effective for treatment of totally drug resistant (TDR) Mycobacterium tuberculosis that shows resistant to all first- and second-line drugs-using an innovative disc agarose channel (DAC) system. Time-lapse images of single bacterial cells under culture conditions with different concentrations of bedaquiline were analysed by image processing software to determine minimum inhibitory concentrations (MICs). Bedaquiline inhibited the growth of TDR M. tuberculosis strains, with MIC values ranging from 0.125 to 0.5 mg/L. The results of the present study demonstrate that bedaquiline, newly approved by the United States Food and Drug Administration (FDA), may offer therapeutic solutions for TDR -TB. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 41 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 15% |
| Student > Master | 6 | 15% |
| Student > Bachelor | 5 | 12% |
| Student > Doctoral Student | 4 | 10% |
| Researcher | 4 | 10% |
| Other | 6 | 15% |
| Unknown | 10 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 9 | 22% |
| Medicine and Dentistry | 7 | 17% |
| Agricultural and Biological Sciences | 4 | 10% |
| Nursing and Health Professions | 3 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Other | 4 | 10% |
| Unknown | 11 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2017.
All research outputs
#19,495,804
of 23,975,976 outputs
Outputs from Journal of Microbiology
#564
of 842 outputs
Outputs of similar age
#240,161
of 313,320 outputs
Outputs of similar age from Journal of Microbiology
#10
of 16 outputs
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So far Altmetric has tracked 842 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
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