| Title |
Bifidobacteria: their impact on gut microbiota composition and their applications as probiotics in infants
|
|---|---|
| Published in |
Applied Microbiology and Biotechnology, November 2013
|
| DOI | 10.1007/s00253-013-5405-9 |
| Pubmed ID | |
| Authors |
Diana Di Gioia, Irene Aloisio, Giuseppe Mazzola, Bruno Biavati |
| Abstract |
This review is aimed at describing the most recent advances in the gut microbiota composition of newborns and infants with a particular emphasis on bifidobacteria. The newborn gut microbiota is quite unstable, whereas after weaning, it becomes more stable and gets closer to the typical adult microbiota. The newborn and infant gut microbiota composition is impaired in several enteric and non-enteric pathologies. The core of this review is the description of the most recent documented applications of bifidobacteria to newborns and infants for their prevention and treatment. Acute diarrhea is the most studied disease for which bifidobacteria are applied with great success, Bifidobacterium longum and Bifidobacterium breve being the most applied species. Moreover, the most recent updates in the use of bifidobacteria for the prevention and treatment of pathologies typical of newborns, such as necrotizing enterocolitis, colics, and streptococcal infections, are presented. In addition, a number of not strictly enteric pathologies have in recent years evidenced a strict correlation with an aberrant gut microbiota in infants, in particular showing a reduced level of bifidobacteria. These diseases represent new potential opportunities for probiotic applications. Among them, allergic diseases, celiac disease, obesity, and neurologic diseases are described in this review. The preliminary use of bifidobacteria in in vitro systems and animal models is summarized as well as preliminary in vivo studies. Only after validation of the results via human clinical trials will the potentiality of bifidobacteria in the prevention and cure of these pathologies be definitely assessed. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 20% |
| Netherlands | 1 | 10% |
| Unknown | 7 | 70% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 80% |
| Scientists | 2 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 334 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| United Kingdom | 2 | <1% |
| Malaysia | 1 | <1% |
| Brazil | 1 | <1% |
| Latvia | 1 | <1% |
| Italy | 1 | <1% |
| Japan | 1 | <1% |
| Denmark | 1 | <1% |
| Greece | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 322 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 55 | 16% |
| Student > Master | 53 | 16% |
| Student > Ph. D. Student | 49 | 15% |
| Student > Bachelor | 43 | 13% |
| Student > Doctoral Student | 18 | 5% |
| Other | 44 | 13% |
| Unknown | 72 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 76 | 23% |
| Medicine and Dentistry | 55 | 16% |
| Biochemistry, Genetics and Molecular Biology | 42 | 13% |
| Immunology and Microbiology | 20 | 6% |
| Nursing and Health Professions | 17 | 5% |
| Other | 38 | 11% |
| Unknown | 86 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2022.
All research outputs
#1,404,438
of 24,119,703 outputs
Outputs from Applied Microbiology and Biotechnology
#77
of 8,034 outputs
Outputs of similar age
#16,015
of 315,791 outputs
Outputs of similar age from Applied Microbiology and Biotechnology
#2
of 86 outputs
Altmetric has tracked 24,119,703 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,034 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.