Title |
How Well Does CAPTURE Translate? An Exploratory Analysis of a COPD Case-Finding Method for Spanish-Speaking Patients
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Published in |
CHEST, April 2017
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DOI | 10.1016/j.chest.2017.03.047 |
Pubmed ID | |
Authors |
Wilson A. Quezada, Beth A. Whippo, Patricia A. Jellen, Nancy K. Leidy, David M. Mannino, Katherine J. Kim, MeiLan K. Han, Julia F. Houfek, Barry Make, Karen G. Malley, Catherine A. Meldrum, Stephen I. Rennard, Barbara P. Yawn, Fernando J. Martinez, Byron M. Thomashow, High-Risk-COPD Screening Study Group∗, R. Graham Barr, Russ P. Bowler, Rebecca Copeland, Tim Dorius, Karen Ishitani, Marge Kurland, James Melson, Randel Plant, Christina Schnell, Jason Shiffermiller, Sonja Stringer, Deb Sumnick, Kyle Textor, Jennifer Underwood, John Walsh |
Abstract |
This study tested the properties of a Spanish translation of CAPTURE™ (COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk) with selective use of peak expiratory flow (PEF). Analyses of data from the Spanish-speaking cohort of the cross-sectional, case-control study used to develop CAPTURE. Translation procedures included forward and backward translation, reconciliation, and cognitive interviewing to assure linguistic and cultural equivalence. Spanish-speaking participants were recruited through one center and designated as Cases (clinically significant COPD: FEV1 < 60% predicted and/or at risk of COPD exacerbation) or Controls (No or mild COPD). Subjects completed a questionnaire booklet that included 44 candidate items, COPD Assessment Test (CAT), and modified Medical Research Council (mMRC) dyspnea question. PEF and spirometry were also performed. N=30 participants: 17 cases; 13 controls. Mean (SD) age: 62.6 (11.49) years; 33% male. CAPTURE-S scores were significantly correlated with PEF (r=-0.78), FEV1/FVC ratio (r=-0.74), FEV1r= (-0.69), FEV1% predicted (r=-0.69), CAT score (r=0.70), and mMRC (r=0.59) (p<0.0001), with significantly higher scores in cases than controls (t=6.16, p<0.0001). PEF significantly correlated with FEV1 (r=0.89), FEV1 % predicted (r=0.79), and FEV1/FVC (r=0.75) (p<0.0001), with significantly lower PEF in cases than controls (t=5.08, p<0.0001). CAPTURE-S score plus PEF differentiated cases and controls with sensitivity = 88.2% and specificity = 92.3%. CAPTURE-S with selective use of PEF appears to be useful for identifying Spanish-speaking patients in need of diagnostic evaluation for clinically significant COPD who may benefit from initiation of COPD treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Venezuela, Bolivarian Republic of | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 47 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 21% |
Student > Bachelor | 6 | 13% |
Researcher | 5 | 11% |
Student > Postgraduate | 4 | 9% |
Student > Doctoral Student | 3 | 6% |
Other | 7 | 15% |
Unknown | 12 | 26% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 17 | 36% |
Nursing and Health Professions | 5 | 11% |
Psychology | 3 | 6% |
Social Sciences | 2 | 4% |
Chemical Engineering | 1 | 2% |
Other | 6 | 13% |
Unknown | 13 | 28% |