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FireProt: web server for automated design of thermostable proteins

Overview of attention for article published in Nucleic Acids Research, April 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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8 X users

Citations

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108 Dimensions

Readers on

mendeley
205 Mendeley
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1 CiteULike
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Title
FireProt: web server for automated design of thermostable proteins
Published in
Nucleic Acids Research, April 2017
DOI 10.1093/nar/gkx285
Pubmed ID
Authors

Milos Musil, Jan Stourac, Jaroslav Bendl, Jan Brezovsky, Zbynek Prokop, Jaroslav Zendulka, Tomas Martinek, David Bednar, Jiri Damborsky

Abstract

There is a continuous interest in increasing proteins stability to enhance their usability in numerous biomedical and biotechnological applications. A number of in silico tools for the prediction of the effect of mutations on protein stability have been developed recently. However, only single-point mutations with a small effect on protein stability are typically predicted with the existing tools and have to be followed by laborious protein expression, purification, and characterization. Here, we present FireProt, a web server for the automated design of multiple-point thermostable mutant proteins that combines structural and evolutionary information in its calculation core. FireProt utilizes sixteen tools and three protein engineering strategies for making reliable protein designs. The server is complemented with interactive, easy-to-use interface that allows users to directly analyze and optionally modify designed thermostable mutants. FireProt is freely available at http://loschmidt.chemi.muni.cz/fireprot.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 205 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 205 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 20%
Researcher 28 14%
Student > Bachelor 28 14%
Student > Master 17 8%
Student > Doctoral Student 9 4%
Other 18 9%
Unknown 63 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 67 33%
Agricultural and Biological Sciences 25 12%
Chemistry 14 7%
Chemical Engineering 6 3%
Engineering 5 2%
Other 20 10%
Unknown 68 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2022.
All research outputs
#5,966,157
of 22,797,621 outputs
Outputs from Nucleic Acids Research
#10,480
of 26,310 outputs
Outputs of similar age
#94,661
of 309,169 outputs
Outputs of similar age from Nucleic Acids Research
#100
of 297 outputs
Altmetric has tracked 22,797,621 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 26,310 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,169 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 297 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.