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Evaluation of the Accuracy of Preoperative MRI in Measuring Myometrial Infiltration in Endometrial Carcinoma

Overview of attention for article published in Pathology & Oncology Research, December 2013
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Title
Evaluation of the Accuracy of Preoperative MRI in Measuring Myometrial Infiltration in Endometrial Carcinoma
Published in
Pathology & Oncology Research, December 2013
DOI 10.1007/s12253-013-9699-9
Pubmed ID
Authors

Katalin Horváth, Imre Pete, Ildikó Vereczkey, Anna Dudnyikova, Mária Gődény

Abstract

The aim of our study was to evaluate the diagnostic performance of magnetic resonance imaging (MRI) in the pretreatment evaluation of myometrium invasion in endometrial cancer. Our retrospective study concerns 89 patients with endometrial cancer, who had preoperative MR evaluation of myometrium invasion and we compared it with histological results. Considering histological type and grade, we had excluded patients with poor prognosis, and separately evaluated those cases where the depth of myometrium invasion is the main prognostic factor determining the choice treatment. Of the 89 cases MRI had accurately evaluated the depth of myometrial invasion in 75 patients. Based on data from all cases, we found the sensitivity of detection of deep myometrial infiltration by MRI (Sv) 71 %, specificity (Sp) 92 %, accuracy (Acc) 84 %, positive predictive value (PPV) 86 % and negative predictive value (NPV) 83 %. Excluding patients with poor prognosis according to histology and grade, these data were Sv 71 %, Sp 95 %, Acc 87 %, PPV 90 %, NPV 84 %. In conclusion, MRI is an efficient diagnostic tool in assessing myometrial infiltration, which is necessary for proper preoperative staging and therapy planning, including evaluation of the necessity of lymphadenectomy. Certain factors may interfere with evaluation of MRI results, thus hindering the precise determination of the level of myometrial infiltration.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 1 8%
Student > Ph. D. Student 1 8%
Researcher 1 8%
Other 1 8%
Student > Master 1 8%
Other 0 0%
Unknown 8 62%
Readers by discipline Count As %
Unspecified 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Social Sciences 1 8%
Neuroscience 1 8%
Medicine and Dentistry 1 8%
Other 0 0%
Unknown 8 62%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2013.
All research outputs
#15,286,644
of 22,733,113 outputs
Outputs from Pathology & Oncology Research
#294
of 710 outputs
Outputs of similar age
#192,779
of 307,131 outputs
Outputs of similar age from Pathology & Oncology Research
#3
of 9 outputs
Altmetric has tracked 22,733,113 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 710 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
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We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.