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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Asymmetric Silica Nanoparticles with Tunable Head–Tail Structures Enhance Hemocompatibility and Maturation of Immune Cells
|
|---|---|
| Published in |
Journal of the American Chemical Society, May 2017
|
| DOI | 10.1021/jacs.6b12622 |
| Pubmed ID | |
| Authors |
Prasanna Lakshmi Abbaraju, Anand Kumar Meka, Hao Song, Yannan Yang, Manasi Jambhrunkar, Jun Zhang, Chun Xu, Meihua Yu, Chengzhong Yu |
| Abstract |
Asymmetric mesoporous silica nanoparticles (MSN) with controllable head-tail structures have been successfully synthesized. The head particle type is tunable (solid or porous) and the tail has dendritic large pores. The tail length and tail coverage on head particles are adjustable. Compared to spherical silica nanoparticles with a solid structure (Stöber spheres) or large-pore symmetrical MSN with fully covered tails, asymmetrical head-tail MSN (HTMSN) show superior hemocompatibility due to reduced membrane deformation of red blood cells and decreased level of reactive oxygen species. Moreover, compared to Stöber spheres, asymmetrical HTMSN exhibit a higher level of uptake and in vitro maturation of immune cells including dendritic cells and macrophage. This study has provided a new family of nanocarriers with potential applications in vaccine development and immunotherapy. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 84 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 26% |
| Student > Master | 8 | 10% |
| Student > Bachelor | 7 | 8% |
| Researcher | 6 | 7% |
| Student > Doctoral Student | 4 | 5% |
| Other | 13 | 15% |
| Unknown | 24 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 18 | 21% |
| Materials Science | 10 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 6% |
| Engineering | 5 | 6% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Other | 15 | 18% |
| Unknown | 27 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2017.
All research outputs
#15,454,502
of 22,965,074 outputs
Outputs from Journal of the American Chemical Society
#55,720
of 62,213 outputs
Outputs of similar age
#194,775
of 310,760 outputs
Outputs of similar age from Journal of the American Chemical Society
#363
of 479 outputs
Altmetric has tracked 22,965,074 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 62,213 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,760 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 479 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.