Title |
Effects of a synbiotic on fecal quality, short-chain fatty acid concentrations, and the microbiome of healthy sled dogs
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Published in |
BMC Veterinary Research, December 2013
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DOI | 10.1186/1746-6148-9-246 |
Pubmed ID | |
Authors |
Jason W Gagné, Joseph J Wakshlag, Kenneth W Simpson, Scot E Dowd, Shalini Latchman, Dawn A Brown, Kit Brown, Kelly S Swanson, George C Fahey |
Abstract |
Sled dogs commonly suffer from diarrhea. Although multiple etiologies exist there are limited field studies using synbiotics as a supplement to prevent or treat diarrhea. The objective of this study was to examine alterations in fecal quality, short-chain fatty acids (SCFA), and the fecal microbiome in two groups of training sled dogs fed a synbiotic or microcrystalline cellulose placebo. Twenty clinically healthy training sled dogs randomized into two cohorts (9 synbiotic-fed, 8 placebo-fed) for a 6 week prospective study were examined. Fecal pH and fecal short chain fatty acid (SCFA) concentrations were measured and tag-encoded FLX 16S rDNA amplicon pyrosequencing (bTEFAP) and quantitative real-time PCR were performed at baseline (10 d prior to the study) and after 2 weeks of treatment with a total treatment time of 6 weeks. Fecal scores for all dogs were assessed at baseline and every day for 6 wk after initiation of treatment. |
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United States | 2 | 29% |
United Kingdom | 1 | 14% |
India | 1 | 14% |
Unknown | 3 | 43% |
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Scientists | 2 | 29% |
Mendeley readers
Geographical breakdown
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United States | 2 | 1% |
Unknown | 132 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 23 | 17% |
Student > Master | 23 | 17% |
Researcher | 19 | 14% |
Student > Bachelor | 14 | 10% |
Other | 11 | 8% |
Other | 15 | 11% |
Unknown | 29 | 22% |
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Medicine and Dentistry | 15 | 11% |
Biochemistry, Genetics and Molecular Biology | 7 | 5% |
Immunology and Microbiology | 5 | 4% |
Other | 12 | 9% |
Unknown | 32 | 24% |