| Title |
Quantifying circulating hypoxia-induced RNA transcripts in maternal blood to determine in uterofetal hypoxic status
|
|---|---|
| Published in |
BMC Medicine, December 2013
|
| DOI | 10.1186/1741-7015-11-256 |
| Pubmed ID | |
| Authors |
Clare Whitehead, Wan Tinn Teh, Susan P Walker, Cheryl Leung, Sonali Mendis, Luke Larmour, Stephen Tong |
| Abstract |
Hypoxia in utero can lead to stillbirth and severe perinatal injury. While current prenatal tests can identify fetuses that are hypoxic, none can determine the severity of hypoxia/acidemia. We hypothesized a hypoxic/acidemic fetus would up-regulate and release hypoxia-induced mRNA from the fetoplacental unit into the maternal circulation, where they can be sampled and quantified. Furthermore, we hypothesized the abundance of hypoxia induced mRNA in the maternal circulation would correlate with severity of fetal hypoxia/acidemia in utero. We therefore examined whether abundance of hypoxia-induced mRNA in the maternal circulation correlates with the degree of fetal hypoxia in utero. |
X Demographics
The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 25% |
| Chile | 2 | 8% |
| France | 2 | 8% |
| Australia | 2 | 8% |
| United States | 2 | 8% |
| Russia | 1 | 4% |
| Venezuela, Bolivarian Republic of | 1 | 4% |
| Spain | 1 | 4% |
| Unknown | 7 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 16 | 67% |
| Practitioners (doctors, other healthcare professionals) | 5 | 21% |
| Scientists | 2 | 8% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 59 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 20% |
| Student > Ph. D. Student | 7 | 12% |
| Student > Master | 7 | 12% |
| Student > Bachelor | 6 | 10% |
| Professor > Associate Professor | 5 | 8% |
| Other | 11 | 19% |
| Unknown | 11 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 34% |
| Agricultural and Biological Sciences | 9 | 15% |
| Nursing and Health Professions | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Engineering | 2 | 3% |
| Other | 4 | 7% |
| Unknown | 16 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 142. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2015.
All research outputs
#252,730
of 23,318,744 outputs
Outputs from BMC Medicine
#217
of 3,508 outputs
Outputs of similar age
#2,383
of 309,896 outputs
Outputs of similar age from BMC Medicine
#2
of 52 outputs
Altmetric has tracked 23,318,744 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,508 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,896 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.