| Title |
Stress, Age, and Immune Function: Toward a Lifespan Approach
|
|---|---|
| Published in |
Journal of Behavioral Medicine, May 2006
|
| DOI | 10.1007/s10865-006-9057-4 |
| Pubmed ID | |
| Authors |
Jennifer E. Graham, Lisa M. Christian, Janice K. Kiecolt-Glaser |
| Abstract |
Both aging processes and psychological stress affect the immune system: Each can dysregulate immune function with a potentially substantial impact on physical health. Worse, the effects of stress and age are interactive. Psychological stress can both mimic and exacerbate the effects of aging, with older adults often showing greater immunological impairment to stress than younger adults. In addition, stressful experiences very early in life can alter the responsiveness of the nervous system and immune system. We review the unique impact of aging and stress on immune function, followed by evidence of interactions between age and stress. Further, we suggest that prenatal or early life stress may increase the likelihood of maladaptive immune responses to stress in late life. An understanding of the interactive effects of stress and age is critical to efforts to determine underlying mechanisms, clarify the directionality of effects, and develop effective interventions in early and late life. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 407 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 3% |
| United Kingdom | 3 | <1% |
| Italy | 2 | <1% |
| Australia | 1 | <1% |
| Slovenia | 1 | <1% |
| Germany | 1 | <1% |
| China | 1 | <1% |
| Mexico | 1 | <1% |
| Japan | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 382 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 75 | 18% |
| Student > Bachelor | 55 | 14% |
| Researcher | 49 | 12% |
| Student > Master | 44 | 11% |
| Student > Doctoral Student | 33 | 8% |
| Other | 76 | 19% |
| Unknown | 75 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 130 | 32% |
| Medicine and Dentistry | 58 | 14% |
| Agricultural and Biological Sciences | 35 | 9% |
| Social Sciences | 23 | 6% |
| Neuroscience | 16 | 4% |
| Other | 51 | 13% |
| Unknown | 94 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2024.
All research outputs
#2,086,708
of 24,980,180 outputs
Outputs from Journal of Behavioral Medicine
#172
of 1,145 outputs
Outputs of similar age
#3,819
of 79,232 outputs
Outputs of similar age from Journal of Behavioral Medicine
#3
of 9 outputs
Altmetric has tracked 24,980,180 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,145 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.0. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 79,232 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.