| Title |
Role of serotonin in fatty acid-induced non-alcoholic fatty liver disease in mice
|
|---|---|
| Published in |
BMC Gastroenterology, December 2013
|
| DOI | 10.1186/1471-230x-13-169 |
| Pubmed ID | |
| Authors |
Yvonne Ritze, Maureen Böhle, Synia Haub, Astrid Hubert, Paul Enck, Stephan Zipfel, Stephan C Bischoff |
| Abstract |
Saturated fatty acids are thought to be of relevance for the development of non-alcoholic fatty liver disease and obesity. However, the underlying mechanisms are poorly understood. In previous studies we found that food-derived carbohydrates such as fructose alter the intestinal serotonergic system while inducing fatty liver disease in mice. Here, we examined the effect of fatty acid quantity (11% versus 15%) and quality (saturated, monounsaturated, or polyunsaturated fatty acids) on hepatic fat accumulation, intestinal barrier and the intestinal serotonergic system. |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Australia | 1 | 2% |
| Unknown | 43 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 16% |
| Student > Bachelor | 5 | 11% |
| Researcher | 5 | 11% |
| Student > Master | 5 | 11% |
| Student > Doctoral Student | 4 | 9% |
| Other | 10 | 22% |
| Unknown | 9 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 9 | 20% |
| Medicine and Dentistry | 8 | 18% |
| Biochemistry, Genetics and Molecular Biology | 7 | 16% |
| Psychology | 3 | 7% |
| Immunology and Microbiology | 2 | 4% |
| Other | 7 | 16% |
| Unknown | 9 | 20% |