| Title |
The frequency of asthma exacerbations and healthcare utilization in patients with asthma from the UK and USA
|
|---|---|
| Published in |
BMC Pulmonary Medicine, April 2017
|
| DOI | 10.1186/s12890-017-0409-3 |
| Pubmed ID | |
| Authors |
Robert Y. Suruki, Jonas B. Daugherty, Nada Boudiaf, Frank C. Albers |
| Abstract |
Asthma exacerbations are frequent in patients with severe disease. This report describes results from two retrospective cohort studies describing exacerbation frequency and risk, emergency department (ED)/hospital re-admissions, and asthma-related costs by asthma severity in the US and UK. Patients with asthma in the US-based Clinformatics™ DataMart Multiplan IMPACT (2010-2011; WEUSKOP7048) and the UK-based Clinical Practice Research Datalink (2009-2011; WEUSKOP7092) databases were categorized by disease severity (Global Initiative for Asthma [GINA]; Step and exacerbation history) during the 12 months pre-asthma medical code (index date). Outcomes included: frequency of exacerbations (asthma-related ED visit, hospitalization, or oral corticosteroid use with an asthma medical code recorded within ±2 weeks) 12 months post-index, asthma-related ED visits/hospitalization, and asthma-related costs 30 days post-index. Risk of a subsequent exacerbation was determined by proportional hazard model. Of the 222,817 and 211,807 patients with asthma included from the US and UK databases, respectively, 12.5 and 8.4% experienced ≥1 exacerbation during the follow-up period. Exacerbation frequency increased with disease severity. Among the 5,167 and 2,904 patients with an asthma-related ED visit/hospitalization in the US and UK databases, respectively, 9.2 and 4.7% had asthma-related re-admissions within 30 days. Asthma-related re-admission rates and costs increased with disease severity, approximately doubling between GINA Step 1 and 5 and in patients with ≥2 versus <2 exacerbations in the previous year. Risk of a subsequent exacerbation increased 32-35% for an exacerbation requiring ED visit/hospitalization versus oral corticosteroids. Increased disease severity was associated with higher exacerbation frequency, ED/hospitalization re-admission, costs and risk of subsequent exacerbation, indicating that these patients require high-intensity post-exacerbation management. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 50% |
| Practitioners (doctors, other healthcare professionals) | 2 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 236 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 236 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 43 | 18% |
| Other | 25 | 11% |
| Student > Bachelor | 18 | 8% |
| Student > Master | 14 | 6% |
| Student > Ph. D. Student | 13 | 6% |
| Other | 42 | 18% |
| Unknown | 81 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 65 | 28% |
| Nursing and Health Professions | 17 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 4% |
| Economics, Econometrics and Finance | 10 | 4% |
| Biochemistry, Genetics and Molecular Biology | 7 | 3% |
| Other | 28 | 12% |
| Unknown | 99 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 June 2021.
All research outputs
#2,153,389
of 22,968,808 outputs
Outputs from BMC Pulmonary Medicine
#116
of 1,943 outputs
Outputs of similar age
#42,774
of 309,813 outputs
Outputs of similar age from BMC Pulmonary Medicine
#4
of 36 outputs
Altmetric has tracked 22,968,808 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,943 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done particularly well, scoring higher than 93% of its peers.
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We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.