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Molecular characterization of lysyl oxidase‐mediated extracellular matrix remodeling during mouse decidualization

Overview of attention for article published in Febs Letters, April 2017
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Title
Molecular characterization of lysyl oxidase‐mediated extracellular matrix remodeling during mouse decidualization
Published in
Febs Letters, April 2017
DOI 10.1002/1873-3468.12645
Pubmed ID
Authors

Shu‐Yun Li, Jia‐qi Yan, Zhuo Song, Yue‐Fang Liu, Min‐Jie Song, Jia‐Wen Qin, Zeng‐Ming Yang, Xiao‐Huan Liang

Abstract

The establishment of decidualization is a prerequisite of successful pregnancy. Lysyl oxidase (Lox) is a copper-containing amine oxidase which catalyzes cross-linking of collagen and elastin in the ECM. Lox is expressed in the subluminal stroma surrounding the implanting blastocyst on day 5 of pregnancy. From days 6 to 8, the signals for Lox mRNA and protein are strongly detected in the decidual cells. The expression of Lox is under the control of estrogen via the GSK-3β/β-catenin/c-myc pathway. Dtprp is decreased by the inhibition of Lox activity. Furthermore, the inhibition of Lox activity decreases stromal cell migration and embryo adhesion. Our findings highlight the crucial role of Lox in endometrial stromal cells and deepen our understanding of decidualization. This article is protected by copyright. All rights reserved.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 17%
Student > Ph. D. Student 2 17%
Unspecified 1 8%
Student > Doctoral Student 1 8%
Researcher 1 8%
Other 0 0%
Unknown 5 42%
Readers by discipline Count As %
Engineering 2 17%
Medicine and Dentistry 2 17%
Unspecified 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Unknown 6 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Febs Letters
#13,421
of 14,374 outputs
Outputs of similar age
#249,230
of 324,469 outputs
Outputs of similar age from Febs Letters
#43
of 69 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,374 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 2nd percentile – i.e., 2% of its peers scored the same or lower than it.
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We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.