Title |
Epigenetic silencing of glutaminase 2 in human liver and colon cancers
|
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Published in |
BMC Cancer, December 2013
|
DOI | 10.1186/1471-2407-13-601 |
Pubmed ID | |
Authors |
Jianbin Zhang, Cheng Wang, Mingquan Chen, Jianping Cao, Ying Zhong, Liting Chen, Han-Ming Shen, Dajing Xia |
Abstract |
Glutaminase 2 (Gls2) is a p53 target gene and is known to play an important role in energy metabolism. Gls2 has been reported to be downregulated in human hepatocellular carcinomas (HCC). However, the underlying mechanism responsible for its downregulation is still unclear. Here, we investigated Gls2 expression and its promoter methylation status in human liver and colon cancers. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Members of the public | 1 | 33% |
Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 44 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 25% |
Student > Ph. D. Student | 9 | 20% |
Student > Master | 6 | 14% |
Student > Doctoral Student | 2 | 5% |
Student > Bachelor | 1 | 2% |
Other | 2 | 5% |
Unknown | 13 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 14 | 32% |
Biochemistry, Genetics and Molecular Biology | 8 | 18% |
Medicine and Dentistry | 6 | 14% |
Environmental Science | 1 | 2% |
Engineering | 1 | 2% |
Other | 0 | 0% |
Unknown | 14 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2013.
All research outputs
#14,184,832
of 22,736,112 outputs
Outputs from BMC Cancer
#3,358
of 8,272 outputs
Outputs of similar age
#176,425
of 307,706 outputs
Outputs of similar age from BMC Cancer
#39
of 104 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,272 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,706 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.