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A review of ketamine in affective disorders: Current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action

Overview of attention for article published in Journal of Affective Disorders, December 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
2 news outlets
blogs
1 blog
twitter
6 X users
patent
2 patents
facebook
3 Facebook pages
wikipedia
5 Wikipedia pages

Citations

dimensions_citation
148 Dimensions

Readers on

mendeley
419 Mendeley
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Title
A review of ketamine in affective disorders: Current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action
Published in
Journal of Affective Disorders, December 2013
DOI 10.1016/j.jad.2013.11.014
Pubmed ID
Authors

Marie Naughton, Gerard Clarke, Olivia F. O′Leary, John F. Cryan, Timothy G. Dinan

Abstract

Recent research has seen low-dose ketamine emerge as a novel, rapid-acting antidepressant. Ketamine, an N-methy-d-aspartate (NMDA) receptor antagonist, leads to effects on the glutamatergic system and abnormalities in this neurotransmittor system are present in depression. This article aims to (1) review the clinical literature on low-dose ketamine as a rapid-acting antidepressant in affective disorders, (2) provide a critical overview of the limitations of ketamine and research attempts to overcome these (3) discuss the proposed mechanisms of action of ketamine and (4) point towards future research directions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 419 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 1%
Brazil 3 <1%
Ireland 1 <1%
Norway 1 <1%
Chile 1 <1%
India 1 <1%
South Africa 1 <1%
Japan 1 <1%
Argentina 1 <1%
Other 0 0%
Unknown 403 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 74 18%
Researcher 60 14%
Student > Ph. D. Student 49 12%
Student > Master 42 10%
Student > Postgraduate 29 7%
Other 89 21%
Unknown 76 18%
Readers by discipline Count As %
Medicine and Dentistry 114 27%
Agricultural and Biological Sciences 49 12%
Psychology 48 11%
Neuroscience 41 10%
Pharmacology, Toxicology and Pharmaceutical Science 16 4%
Other 51 12%
Unknown 100 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2023.
All research outputs
#1,228,944
of 25,374,917 outputs
Outputs from Journal of Affective Disorders
#735
of 10,145 outputs
Outputs of similar age
#13,158
of 320,160 outputs
Outputs of similar age from Journal of Affective Disorders
#6
of 85 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,145 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.5. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,160 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.