Title |
Resistant Hypertension and Sleep Apnea: Pathophysiologic Insights and Strategic Management
|
---|---|
Published in |
Current Diabetes Reports, November 2010
|
DOI | 10.1007/s11892-010-0161-z |
Pubmed ID | |
Authors |
Stephen K. Williams, Joseph Ravenell, Girardin Jean-Louis, Ferdinand Zizi, James A. Underberg, Samy I. McFarlane, Gbenga Ogedegbe |
Abstract |
Resistant hypertension is common among adults with hypertension affecting up to 30% of patients. The treatment of resistant hypertension is important because suboptimal blood pressure control is the leading preventable cause of death worldwide. A frequent comorbid condition in patients with resistant hypertension is obstructive sleep apnea. The pathophysiology of sleep apnea-associated hypertension is characterized by sustained adrenergic activation and volume retention often posing treatment challenges in patients with resistant hypertension. This review will address some of the epidemiologic data associating apnea with the pathogenesis of resistant hypertension. Diagnosis and management of apnea and its associated hypertension will also be considered. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 5 | 21% |
Student > Master | 4 | 17% |
Student > Doctoral Student | 2 | 8% |
Student > Bachelor | 2 | 8% |
Lecturer | 1 | 4% |
Other | 4 | 17% |
Unknown | 6 | 25% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 33% |
Nursing and Health Professions | 3 | 13% |
Neuroscience | 2 | 8% |
Psychology | 1 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Other | 2 | 8% |
Unknown | 7 | 29% |