| Title |
P. aeruginosa colonization at ICU admission as a risk factor for developing P. aeruginosa ICU pneumonia
|
|---|---|
| Published in |
Antimicrobial Resistance & Infection Control, April 2017
|
| DOI | 10.1186/s13756-017-0197-9 |
| Pubmed ID | |
| Authors |
Fleur P. Paling, Martin Wolkewitz, Pieter Depuydt, Liesbet de Bus, Frangiscos Sifakis, Marc J. M. Bonten, Jan A. J. W. Kluytmans |
| Abstract |
To determine the incidence of P. aeruginosa (PA) ICU pneumonia and its independent association with PA colonization at ICU admission. This was a post-hoc analysis of a prospectively collected cohort study. Adult ICU patients with a length of stay of ≥48 h were included and assessed for microbiologically confirmed PA ICU pneumonia. Multivariate survival analysis was performed, including the covariates age, gender, PA colonization at ICU admission, ICU admission specialty and mechanical ventilation at ICU admission, while taking into account the effect of competing risks. We included 5093 patients, 2447 (48%) were tested for colonization; of those 226 (9.2%) were PA colonized at ICU admission. The incidence of PA ICU pneumonia was 1.34% (n = 68). PA colonization was an independent risk factor (subdistribution hazard ratio [SHR] 8.8; 95% confidence interval [CI] 4.9-15.7), as was mechanical ventilation (SHR 5.3, 95% CI 2.7-10.6). In this study the incidence of P. aeruginosa ICU pneumonia was 1.34%. Hazard ratios for PA colonized patients compared to non-colonized to develop PA ICU pneumonia were 8.8. The high risk associated with P. aeruginosa colonization for subsequent infection may offer a target for future interventions. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 29% |
| Student > Master | 3 | 18% |
| Researcher | 2 | 12% |
| Student > Bachelor | 1 | 6% |
| Student > Doctoral Student | 1 | 6% |
| Other | 2 | 12% |
| Unknown | 3 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 4 | 24% |
| Medicine and Dentistry | 3 | 18% |
| Nursing and Health Professions | 2 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 12% |
| Agricultural and Biological Sciences | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 4 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2017.
All research outputs
#19,512,854
of 24,003,070 outputs
Outputs from Antimicrobial Resistance & Infection Control
#1,200
of 1,347 outputs
Outputs of similar age
#240,161
of 313,394 outputs
Outputs of similar age from Antimicrobial Resistance & Infection Control
#25
of 26 outputs
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