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Characterization of Sgo1 expression in developing and adult mouse

Overview of attention for article published in Gene Expression Patterns, April 2017
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Citations

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Title
Characterization of Sgo1 expression in developing and adult mouse
Published in
Gene Expression Patterns, April 2017
DOI 10.1016/j.gep.2017.04.004
Pubmed ID
Authors

Andrew T. Song, Antonella Galli, Severine Leclerc, Stanley Nattel, Craig Mandato, Gregor Andelfinger

Abstract

SGO1 has been characterized in its function in correct cell division and its role in centrosome cohesion in the nucleus. However, its organ-specific maturation-related expression pattern in vivo remains largely uncharacterized. Here, we show clear SGO1 expression in post-developmental neuronal cells and cytoplasmic localisation in nucleated cells with a transgenic mice model and immunohistochemistry of wild type mice. We demonstrate extranuclear expression of Sgo1 in the developing heart and gut, which have been shown to be dysregulated in humans with homozygous SGO1 mutation. Additionally, we show Sgo1 expression in select population of retinal cells in developing and post-developmental retina. Our expression analysis strongly suggests that the function of SGO1 goes beyond its well characterized role in cell division.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 31%
Student > Ph. D. Student 3 23%
Student > Bachelor 2 15%
Other 2 15%
Librarian 1 8%
Other 1 8%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 31%
Nursing and Health Professions 2 15%
Arts and Humanities 1 8%
Agricultural and Biological Sciences 1 8%
Computer Science 1 8%
Other 3 23%
Unknown 1 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2017.
All research outputs
#15,742,933
of 25,382,440 outputs
Outputs from Gene Expression Patterns
#190
of 386 outputs
Outputs of similar age
#178,568
of 324,890 outputs
Outputs of similar age from Gene Expression Patterns
#2
of 6 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 386 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,890 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.