| Title |
Cat-rodent Toxoplasma gondii Type II-variant circulation and limited genetic diversity on the Island of Fernando de Noronha, Brazil
|
|---|---|
| Published in |
Parasites & Vectors, May 2017
|
| DOI | 10.1186/s13071-017-2150-4 |
| Pubmed ID | |
| Authors |
Jean Carlos Ramos Silva, Fernando Ferreira, Ricardo Augusto Dias, Daniel Ajzenberg, Maria Fernanda Vianna Marvulo, Fernando Jorge Rodrigues Magalhães, Carlos Diógenes Ferreira Lima Filho, Solange Oliveira, Herbert Sousa Soares, Thais Ferreira Feitosa, Juliana Aizawa, Leucio Câmara Alves, Rinaldo Aparecido Mota, Jitender Prakask Dubey, Solange Maria Gennari, Hilda Fátima Jesus Pena |
| Abstract |
In Brazil, studies on animals and humans in mainland areas have shown that most strains of Toxoplasma gondii are pathogenic to mice and exhibit great genetic variability. In this study, using a set of 11 PCR-RFLP and 15 microsatellite markers, we isolated and genetically characterised T. gondii strains from one cat and three rats on Fernando de Noronha Island. The cat had antibodies to T. gondii, which were revealed using a modified agglutination test (MAT, cut-off 1:25) and the seroprevalence among the 46 rodents was 15.2%. Viable T. gondii was isolated from one cat (TgCatBrFN1), two brown rats (TgRatnoBrFN1 and TgRatnoBrFN2) and one black rat (TgRatraBrFN1). Unlike the strains from mainland Brazil, these isolates were not pathogenic to outbred mice. The genotypes of these strains were compared with strains previously isolated on the island and in mainland Brazil. The analysis based on microsatellite data showed a limited genetic diversity of T. gondii on Fernando de Noronha Island with the majority of strains clustered into the following three groups: type II, III, and Caribbean 1. There was little variation among strains within the same group, suggesting that the majority of strains circulating on Fernando de Noronha are derived from only a few strains that were recently introduced to the island, likely from imported cats. Except for the strain belonging to the Caribbean 1 group that originates from northeast Brazil, there was little evidence that strains from the other groups were introduced to Fernando de Noronha via mainland Brazil. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 57 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 12 | 21% |
| Researcher | 8 | 14% |
| Student > Ph. D. Student | 8 | 14% |
| Student > Bachelor | 5 | 9% |
| Other | 4 | 7% |
| Other | 11 | 19% |
| Unknown | 9 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Veterinary Science and Veterinary Medicine | 17 | 30% |
| Agricultural and Biological Sciences | 11 | 19% |
| Environmental Science | 3 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Medicine and Dentistry | 3 | 5% |
| Other | 5 | 9% |
| Unknown | 15 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2018.
All research outputs
#13,551,243
of 22,968,808 outputs
Outputs from Parasites & Vectors
#2,475
of 5,487 outputs
Outputs of similar age
#158,809
of 310,917 outputs
Outputs of similar age from Parasites & Vectors
#78
of 147 outputs
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