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Could ethanol-induced alterations in the expression of glutamate transporters in testes contribute to the effect of paternal drinking on the risk of abnormalities in the offspring?

Overview of attention for article published in Medical Hypotheses, November 2016
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Title
Could ethanol-induced alterations in the expression of glutamate transporters in testes contribute to the effect of paternal drinking on the risk of abnormalities in the offspring?
Published in
Medical Hypotheses, November 2016
DOI 10.1016/j.mehy.2016.11.015
Pubmed ID
Authors

Mohammed Abul Kashem, Aven Lee, David V. Pow, Omar Šerý, Vladimir J. Balcar

Abstract

It has been known that a preconception paternal alcoholism impacts adversely on the offspring but the mechanism of the effect is uncertain. Several findings suggest that there are signalling systems in testis that are analogous to those known to be altered by alcoholism in brain. We propose that chronic alcohol affects these systems in a manner similar to that in brain. Specifically, we hypothesise that excessive alcohol may disturb glutamatergic-like signalling in testis by increasing expression of the glutamate transporter GLAST (EAAT1). We discuss ways how to test the hypothesis as well as potential significance of some of the tests as tools in the diagnostics of chronic alcoholism.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 23%
Researcher 2 15%
Student > Bachelor 1 8%
Lecturer 1 8%
Student > Master 1 8%
Other 1 8%
Unknown 4 31%
Readers by discipline Count As %
Neuroscience 2 15%
Psychology 2 15%
Nursing and Health Professions 1 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Agricultural and Biological Sciences 1 8%
Other 0 0%
Unknown 6 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2017.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Medical Hypotheses
#3,768
of 4,635 outputs
Outputs of similar age
#311,930
of 415,343 outputs
Outputs of similar age from Medical Hypotheses
#30
of 43 outputs
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