| Title |
Nanomedicine advances in toxoplasmosis: diagnostic, treatment, and vaccine applications
|
|---|---|
| Published in |
Parasitology Research, May 2017
|
| DOI | 10.1007/s00436-017-5458-2 |
| Pubmed ID | |
| Authors |
João Paulo Assolini, Virginia Márcia Concato, Manoela Daiele Gonçalves, Amanda Cristina Machado Carloto, Ivete Conchon-Costa, Wander Rogério Pavanelli, Francine Nesello Melanda, Idessania Nazareth Costa |
| Abstract |
Toxoplasmosis is an infectious disease caused by the intracellular parasite Toxoplasma gondii that affects about one third of the world's population. The diagnosis of this disease is carried out by parasite isolation and host antibodies detection. However, the diagnosis presents problems in regard to test sensitivity and specificity. Currently, the most effective T. gondii treatment is a combination of pyrimethamine and sulfadiazine, although both drugs are toxic to the host. In addition to the problems that compromise the effective diagnosis and treatment of toxoplasmosis, there are no reports or indications of any vaccine capable of fully protecting against this infection. Nanomaterials, smaller than 1000 nm, are currently being investigated as an alternative tool in the management of T. gondii infection. This article reviews how recent nanotechnology advances indicate the utility of nanomaterials in toxoplasmosis diagnosis, treatment, and vaccine development. |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 75 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 15% |
| Student > Bachelor | 10 | 13% |
| Student > Ph. D. Student | 8 | 11% |
| Student > Doctoral Student | 7 | 9% |
| Professor | 4 | 5% |
| Other | 13 | 17% |
| Unknown | 22 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 13% |
| Biochemistry, Genetics and Molecular Biology | 10 | 13% |
| Veterinary Science and Veterinary Medicine | 6 | 8% |
| Medicine and Dentistry | 6 | 8% |
| Nursing and Health Professions | 5 | 7% |
| Other | 13 | 17% |
| Unknown | 25 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2017.
All research outputs
#5,932,393
of 22,971,207 outputs
Outputs from Parasitology Research
#410
of 3,798 outputs
Outputs of similar age
#93,947
of 310,732 outputs
Outputs of similar age from Parasitology Research
#7
of 73 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 3,798 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,732 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.