| Title |
Multicenter clinical evaluation of a multi-dose formulation of propofol in the dog
|
|---|---|
| Published in |
BMC Veterinary Research, December 2013
|
| DOI | 10.1186/1746-6148-9-261 |
| Pubmed ID | |
| Authors |
Khursheed R Mama, James S Gaynor, Ralph C Harvey, Sheilah A Robertson, Robbin L Koenig, Elizabeth M Cozzi |
| Abstract |
Propofol is a widely used injectable anesthetic agent for induction and short-term maintenance in dogs. A multi-dose formulation of propofol (MDP) has been developed which includes 2% benzyl alcohol as a preservative. In order to document the use of the product under clinical conditions, MDP was tested in a prospective clinical trial conducted at six sites within the United States. One hundred thirty-eight healthy, client-owned dogs were assigned to one of six treatment groups based on premedicants (none, acepromazine/buprenorphine, midazolam/buprenorphine, medetomidine/buprenorphine) and maintenance agents (MDP, inhaled anesthetic). Anesthesia was induced by the intravenous administration of MDP given to effect. Physiological indices including heart rate, respiratory rate and blood pressure were monitored prior to and during anesthesia induction, maintenance and recovery. Adverse events, defined for severity by pre-established limits of these physiological values, as well as side effects, defined as any observation outside the normal range, were noted. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Austria | 1 | 3% |
| Unknown | 31 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 21% |
| Student > Master | 6 | 18% |
| Student > Bachelor | 4 | 12% |
| Student > Postgraduate | 3 | 9% |
| Other | 2 | 6% |
| Other | 3 | 9% |
| Unknown | 8 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Veterinary Science and Veterinary Medicine | 11 | 33% |
| Medicine and Dentistry | 6 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
| Neuroscience | 2 | 6% |
| Social Sciences | 2 | 6% |
| Other | 2 | 6% |
| Unknown | 8 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 January 2014.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from BMC Veterinary Research
#2,610
of 3,298 outputs
Outputs of similar age
#282,173
of 320,883 outputs
Outputs of similar age from BMC Veterinary Research
#46
of 54 outputs
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