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Toxicity management for patients receiving novel T-cell engaging therapies

Overview of attention for article published in Current opinion in pediatrics, February 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

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3 X users
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7 patents

Citations

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129 Dimensions

Readers on

mendeley
115 Mendeley
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Title
Toxicity management for patients receiving novel T-cell engaging therapies
Published in
Current opinion in pediatrics, February 2014
DOI 10.1097/mop.0000000000000043
Pubmed ID
Authors

David M. Barrett, David T. Teachey, Stephan A. Grupp

Abstract

Recent clinical trials using T-cell engaging immunotherapies such as bispecific antibodies which target T cells and tumor cells, as well as engineered T cells that express targeting and activation molecules known as chimeric antigen receptors, have demonstrated powerful proof of concept. These therapies result in a significant degree of immune activation in the patient, which has correlated with greatly increased efficacy but also with notable toxicity. These therapies produce nonphysiologic T-cell activation, which is the hallmark of these new, highly active treatments.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 114 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 17%
Student > Ph. D. Student 15 13%
Student > Master 13 11%
Student > Bachelor 10 9%
Other 10 9%
Other 17 15%
Unknown 31 27%
Readers by discipline Count As %
Medicine and Dentistry 29 25%
Biochemistry, Genetics and Molecular Biology 12 10%
Agricultural and Biological Sciences 12 10%
Immunology and Microbiology 10 9%
Pharmacology, Toxicology and Pharmaceutical Science 8 7%
Other 16 14%
Unknown 28 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2023.
All research outputs
#2,637,305
of 25,540,105 outputs
Outputs from Current opinion in pediatrics
#119
of 1,444 outputs
Outputs of similar age
#29,898
of 323,452 outputs
Outputs of similar age from Current opinion in pediatrics
#2
of 11 outputs
Altmetric has tracked 25,540,105 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,444 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,452 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.