| Title |
Mutational analysis of Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in the interior division of Sabah, Malaysia
|
|---|---|
| Published in |
Malaria Journal, December 2013
|
| DOI | 10.1186/1475-2875-12-445 |
| Pubmed ID | |
| Authors |
Tiek Ying Lau, Mersumpin Sylvi, Timothy William |
| Abstract |
The sulphadoxine/pyrimethamine (SDX/PYR) combination had been chosen to treat uncomplicated falciparum malaria in Malaysia for more than 30 years. Non-silent mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes are responsible for the resistance to pyrimethamine and sulphadoxine, respectively. This study reports the mutational analysis of pfdhfr and pfdhps in single Plasmodium falciparum infection isolates from the interior division of Sabah, Malaysian Borneo. |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 57 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 22% |
| Student > Ph. D. Student | 9 | 16% |
| Lecturer | 5 | 9% |
| Researcher | 4 | 7% |
| Other | 4 | 7% |
| Other | 10 | 17% |
| Unknown | 13 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 13 | 22% |
| Biochemistry, Genetics and Molecular Biology | 10 | 17% |
| Immunology and Microbiology | 5 | 9% |
| Medicine and Dentistry | 4 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Other | 10 | 17% |
| Unknown | 13 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2013.
All research outputs
#13,399,716
of 22,738,543 outputs
Outputs from Malaria Journal
#3,506
of 5,549 outputs
Outputs of similar age
#165,780
of 306,799 outputs
Outputs of similar age from Malaria Journal
#41
of 73 outputs
Altmetric has tracked 22,738,543 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,549 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,799 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.