Title |
ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas
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Published in |
Gynecologic Oncology, August 2013
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DOI | 10.1016/j.ygyno.2013.07.107 |
Pubmed ID | |
Authors |
Sharon E. Johnatty, Jonathan Beesley, Bo Gao, Xiaoqing Chen, Yi Lu, Matthew H. Law, Michelle J. Henderson, Amanda J. Russell, Ellen L. Hedditch, Catherine Emmanuel, Sian Fereday, Penelope M. Webb, Australian Ovarian Cancer Study Group, Ellen L. Goode, Robert A. Vierkant, Brooke L. Fridley, Julie M Cunningham, Peter A. Fasching, Matthias W. Beckmann, Arif B. Ekici, Estrid Hogdall, Susanne K. Kjaer, Allan Jensen, Claus Hogdall, Robert Brown, Jim Paul, Sandrina Lambrechts, Evelyn Despierre, Ignace Vergote, Jenny Lester, Beth Y. Karlan, Florian Heitz, Andreas du Bois, Philipp Harter, Ira Schwaab, Yukie Bean, Tanja Pejovic, Douglas A. Levine, Marc T. Goodman, Michael E. Camey, Pamela J. Thompson, Galina Lurie, Joellen Shildkraut, Andrew Berchuck, Kathryn L. Terry, Daniel W. Cramer, Murray D. Norris, Michelle Haber, Stuart MacGregor, Anna deFazio, Georgia Chenevix-Trench |
Abstract |
ABCB1 encodes the multi-drug efflux pump P-glycoprotein (P-gp) and has been implicated in multi-drug resistance. We comprehensively evaluated this gene and flanking regions for an association with clinical outcome in epithelial ovarian cancer (EOC). |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Mexico | 1 | 1% |
Romania | 1 | 1% |
Australia | 1 | 1% |
Unknown | 79 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 16 | 20% |
Student > Ph. D. Student | 11 | 13% |
Student > Bachelor | 8 | 10% |
Other | 8 | 10% |
Student > Postgraduate | 6 | 7% |
Other | 16 | 20% |
Unknown | 17 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 23% |
Agricultural and Biological Sciences | 16 | 20% |
Biochemistry, Genetics and Molecular Biology | 10 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Computer Science | 3 | 4% |
Other | 8 | 10% |
Unknown | 22 | 27% |