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Effects of Combinational CYP3A5 6986A>G Polymorphism in Graft Liver and Native Intestine on the Pharmacokinetics of Tacrolimus in Liver Transplant Patients

Overview of attention for article published in Therapeutic Drug Monitoring, August 2014
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3 X users

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28 Mendeley
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Title
Effects of Combinational CYP3A5 6986A>G Polymorphism in Graft Liver and Native Intestine on the Pharmacokinetics of Tacrolimus in Liver Transplant Patients
Published in
Therapeutic Drug Monitoring, August 2014
DOI 10.1097/ftd.0000000000000032
Pubmed ID
Authors

Jefferson A. Buendia, Guillermo Bramuglia, Christine E. Staatz

Abstract

Many studies have reported reduced tacrolimus dose-adjusted exposure in individuals expressing the CYP3A5*1 allele. A meta-analyses of the current data may help characterize the extent of impact this polymorphism has on tacrolimus pharmacokinetics in adult liver transplant recipients and whether donor or recipient genotype is the most influential factor.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 11%
Librarian 2 7%
Student > Doctoral Student 2 7%
Student > Bachelor 2 7%
Other 2 7%
Other 8 29%
Unknown 9 32%
Readers by discipline Count As %
Medicine and Dentistry 9 32%
Pharmacology, Toxicology and Pharmaceutical Science 4 14%
Biochemistry, Genetics and Molecular Biology 3 11%
Agricultural and Biological Sciences 2 7%
Social Sciences 1 4%
Other 0 0%
Unknown 9 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2014.
All research outputs
#16,048,009
of 25,374,647 outputs
Outputs from Therapeutic Drug Monitoring
#922
of 1,787 outputs
Outputs of similar age
#128,669
of 240,209 outputs
Outputs of similar age from Therapeutic Drug Monitoring
#8
of 19 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,787 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,209 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.