| Title |
S100A6 protein: functional roles
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, April 2017
|
| DOI | 10.1007/s00018-017-2526-9 |
| Pubmed ID | |
| Authors |
Rosario Donato, Guglielmo Sorci, Ileana Giambanco |
| Abstract |
S100A6 protein belongs to the A group of the S100 protein family of Ca(2+)-binding proteins. It is expressed in a limited number of cell types in adult normal tissues and in several tumor cell types. As an intracellular protein, S100A6 has been implicated in the regulation of several cellular functions, such as proliferation, apoptosis, the cytoskeleton dynamics, and the cellular response to different stress factors. S100A6 can be secreted/released by certain cell types which points to extracellular effects of the protein. RAGE (receptor for advanced glycation endproducts) and integrin β1 transduce some extracellular S100A6's effects. Dosage of serum S100A6 might aid in diagnosis in oncology. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 75 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 23% |
| Student > Doctoral Student | 11 | 15% |
| Student > Bachelor | 9 | 12% |
| Student > Master | 9 | 12% |
| Researcher | 6 | 8% |
| Other | 5 | 7% |
| Unknown | 18 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 22 | 29% |
| Medicine and Dentistry | 13 | 17% |
| Agricultural and Biological Sciences | 8 | 11% |
| Immunology and Microbiology | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Other | 5 | 7% |
| Unknown | 21 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2017.
All research outputs
#19,201,293
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#3,458
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Outputs of similar age
#237,485
of 311,546 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#35
of 44 outputs
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